SAB5701882

Anti-Phospho-VEGF Receptor 2-Y1175 antibody produced in rabbit

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: liquid
• reatividade de espécies: human
• concentração: 0.94 mg/mL
• técnica(s): western blot: 1:500-1:2000
• nº de adesão UniProt: P35968
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr1175)
• Informações sobre genes: human ... KDR(3791)

Descrição

Descrição geral

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Imunogênio

A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2.

forma física

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable