SAB5500149
Rabbit IgG Negative Control
clone SP137, recombinant, expressed in proprietary host, affinity isolated antibody
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100 μL
R$ 1.431,00
R$ 1.431,00
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100 μL
R$ 1.431,00
About This Item
Código UNSPSC:
12352203
NACRES:
NA.42
R$ 1.431,00
Check Cart for Availability
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
recombinante
expressed in proprietary host
conjugado
unconjugated
forma do anticorpo
affinity isolated antibody
tipo de produto de anticorpo
primary antibodies
clone
SP137, monoclonal
técnica(s)
immunohistochemistry: 1:100
Isotipo
IgG
Condições de expedição
wet ice
temperatura de armazenamento
2-8°C
modificação pós-traducional do alvo
unmodified
Descrição geral
Immunoglobulin G (IgG) belongs to immunoglobulin family and consists of gamma (γ) heavy chain in the constant (C) region. IgG is a widely expressed serum antibody. Monomeric structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50 kDa and 25 kDa respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named γ1, γ2, γ3, and γ4, respectively. IgG is produced and released from CD5+B cells, the predominant lymphocytes in the neonatal cell repertoire. Maternal IgG is the only antibody transported across the placenta to the fetus. Maternal IgG passively immunizes the infants.
The Negative Control is a recombinant rabbit monoclonal antibody against a small molecule, which is normally not present in human or animal. The product will not cross-react with human tissues when used at the recommended concentration.
Aplicação
Rabbit IgG Negative Control has been used as a negative control to evaluate the effectiveness and safety of recombinant human interleukin-11 (IL-11) for treatment of idiopathic thrombocytopenic purpura.
Características e benefícios
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
forma física
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Analysis of clinical effects and mechanism of recombinant human interleukin-11 with glucocorticoids for treatment of idiopathic thrombocytopenic purpura.
Wu X, et al.
Experimental and Therapeutic Medicine, 13(2), 519-522 (2017)
Liang Chen et al.
JCI insight, 9(12) (2024-05-23)
DC inhibitory receptor (DCIR) is a C-type lectin receptor selectively expressed on myeloid cells, including monocytes, macrophages, DCs, and neutrophils. Its role in immune regulation has been implicated in murine models and human genome-wide association studies, suggesting defective DCIR function
Xifeng Wu et al.
Experimental and therapeutic medicine, 13(2), 519-522 (2017-03-30)
The aim of the present study was to evaluate the effectiveness and safety of recombinant human interleukin-11 (IL-11) with glucocorticoids for treatment of adult idiopathic thrombocytopenic purpura (ITP) and the regulatory effect on immune mechanisms. A total of 80 patients
P Casali et al.
Current topics in microbiology and immunology, 210, 167-179 (1996-01-01)
Natural antibodies arise independently of known antigenic stimulation, are mostly IGM, polyreactive, and are generally encoded by V genes in germline configuration. Polyreactive IgM natural antibodies are produced by mainly B-1 cells which account for most of the B cell
Human placental Fc receptors and the transmission of antibodies from mother to fetus.
Simister NE and Story CM
Journal of Reproductive Immunology, 37(1), 1-23 (1997)
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