SAB5200898

Monoclonal Anti-Glun2A/Nr2A - Apc antibody produced in mouse

clone S327-95, purified immunoglobulin

• Sinônimo(s): Anti-GRIN2A, Anti-HNR2A, Anti-NMDA 2A
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• conjugado: Allophycocyanin conjugate
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: S327-95, monoclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen predicted mol wt 170 kDa
• reatividade de espécies: human, rat, mouse
• concentração: 1 mg/mL
• técnica(s): immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgG2a
• nº de adesão NCBI: NP_036705.3
• nº de adesão UniProt: Q12879
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: rat ... Grin2a(24409)

Descrição

Descrição geral

The GRIN2A (glutamate ionotropic receptor NMDA (N-methyl-D-aspartate) type subunit 2A) gene is mapped to human chromosome 16p13.2. It codes for a transmembrane ligand-gated ion channel called N-methyl-D-aspartate glutamate receptor α2 subunit.

Imunogênio

Fusion protein amino acids 75-325 (extracellular N-terminus) of rat GluN2A/NR2A

Ações bioquímicas/fisiológicas

The GRIN2A (glutamate ionotropic receptor NMDA (N-methyl-D-aspartate) type subunit 2A) gene is associated with focal epilepsy and impaired speech. NMDA glutamate receptor α2 subunit is involved in neuron development, maintains synaptic plasticity and is associated with memory. GRIN2A is related to schizophrenia and Alzheimer′s disease. Mutations in GRIN2A gene upregulates NMDA action and might lead to melanoma tumors. NMDA participates in apoptosis and proliferation of cancer cells.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

PBS pH7.4, 50% glycerol, 0.09% sodium azide

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable