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SAB5200110

Sigma-Aldrich

Anti-AQP2 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

Sinônimo(s):

Anti-AQP-CD, Anti-AQP2, Anti-AQPCD, Anti-Aquaporin 2

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous glycerol solution

peso molecular

antigen predicted mol wt 28.8 kDa

reatividade de espécies

human, mouse, rat

concentração

1 mg/mL

técnica(s)

indirect immunofluorescence: suitable
western blot: suitable

nº de adesão NCBI

NP_037041.2

nº de adesão UniProt

P41181

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

rat ... Aqp2(25386)

Categorias relacionadas

Descrição geral

The gene ID of the protein aquaporin-2 (AQP2) is 25386.

Especificidade

Detects ~28.8 kDa. May detect larger glycosylated bands ~35-50 kDa.

Imunogênio

C-terminal peptide

Ações bioquímicas/fisiológicas

Aquaporin 2 (AQP2) takes part in maintaining the water balance in cells. A high concentration of the protein has been observed in rats during hypothyroidism.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

PBS, pH 7..4, 50% glycerol, and 0.09% sodium azide

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Lorena I Sarati et al.
Metabolism: clinical and experimental, 62(9), 1287-1295 (2013-05-28)
Hypothyroid state and aging are associated with impairment in water reabsorption and changes in aquaporin water channel type 2 (AQP2). Nitric oxide (NO) is involved in AQP2 trafficking to the apical plasma membrane in medullary collecting duct cells. The purpose
Salvador Cazorla-Vázquez et al.
Cells, 12(15) (2023-08-11)
Adhesion G protein-coupled receptors (aGPCRs) comprise the second-largest class of GPCRs, the most common target for approved pharmacological therapies. aGPCRs play an important role in development and disease and have recently been associated with the kidney. Several aGPCRs are expressed
Peter Kösters et al.
Cells, 13(10) (2024-05-24)
Uncovering the function of understudied G protein-coupled receptors (GPCRs) provides a wealth of untapped therapeutic potential. The poorly understood adhesion GPCR Gpr126 (Adgrg6) is widely expressed in developing kidneys. In adulthood, Gpr126 expression is enriched in parietal epithelial cells (PECs)
William J Monis et al.
The Journal of cell biology, 216(7), 2131-2150 (2017-06-04)
Primary cilia perceive the extracellular environment through receptors localized in the ciliary membrane, but mechanisms directing specific proteins to this domain are poorly understood. To address this question, we knocked down proteins potentially important for ciliary membrane targeting and determined
Naohiro Nomura et al.
American journal of physiology. Cell physiology, 307(7), C597-C605 (2014-06-20)
A reduction or loss of plasma membrane aquaporin 2 (AQP2) in kidney principal cells due to defective vasopressin (VP) signaling through the VP receptor causes excessive urine production, i.e., diabetes insipidus. The amount of AQP2 on the plasma membrane is

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