SAB5200104

Anti-SLC12A3 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

• Sinônimo(s): Anti-NCC, Anti-Slc12a3
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous glycerol solution
• peso molecular: antigen predicted mol wt 160 kDa
• reatividade de espécies: human, rat, mouse
• concentração: 1 mg/mL
• técnica(s): western blot: suitable
• nº de adesão NCBI: NP_000330; NP_062218
• nº de adesão UniProt: P55017
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... SLC12A3(6559) ; rat ... Slc12a3(54300)

Descrição

Descrição geral

Solute carrier family 12 member 3 (SLC12A3) is also known as thiazide-sensitive Na⁺-Cl^- cotransporter (NCCT). It is expressed in the apical cells of the distal convoluted tubule. The gene encoding this 1021 amino acid protein is localized on human chromosome 16q13. The gene ID for the protein is 6559.

Especificidade

Detects ~160 kDa.

Imunogênio

AA74-95 (rat), 76-97 (hum)

Ações bioquímicas/fisiológicas

Solute carrier family 12 member 3 (SLC12A3) is one of the major components of the sodium chloride reabsorption pathway. It controls the Cl^- concentration and is also involved in the transepithelial ion absorption and secretion. Mutations in the gene encoding SLC12A3 have been associated with Gitelman syndrome.

This Na-Cl cotransporter is associated with maintaining blood pressure.

Características e benefícios

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forma física

PBS, 50% glycerol, and 0.09% sodium azide

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable