SAB4504326

Anti-phospho-Vitamin D Receptor (pSer²⁰⁸) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: antigen 48 kDa
• reatividade de espécies: mouse, rat, human
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:10000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• nº de adesão NCBI: P11473
• nº de adesão UniProt: P11473
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer208)
• Informações sobre genes: human ... VDR(7421)

Descrição

Descrição geral

VDR (vitamin D receptor) or vitamin D3 receptor is a member of the steroid and thyroid hormone receptors superfamily of trans-acting transcriptional regulatory factors. It is an intracellular polypeptide of 50-60 kDa. This receptor is composed of a highly conserved cysteine, lysine, and arginine-rich DNA-binding domain, and a hydrophobic ligand-binding domain in its C-terminal. It shares size and sequence similarity to thyroid hormone receptor. VDR gene is localized to human chromosome 12q12-q14.

Imunogênio

The antiserum was produced against synthesized peptide derived from human Vitamin D Receptor around the phosphorylation site of Ser208.

Immunogen Range: 181-230

Ações bioquímicas/fisiológicas

VDR (vitamin D receptor) binds with its ligand vitamin D3, and acts upon the target cell nuclei to induce various biological effects. Vitamin D3 is also thought to have immunomodulatory effects, and gene polymorphisms are linked with pertussis. The variants might affect the immune response and clinical outcome of Bordetella pertussis infection.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable