SAB4504264

Anti-phospho-RAD51 (pTyr³¹⁵) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 36 kDa
• reatividade de espécies: rat, human, mouse
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:10000; western blot: 1:500-1:1000
• nº de adesão NCBI: Q06609
• nº de adesão UniProt: Q06609
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr315)
• Informações sobre genes: human ... RAD51(5888)

Descrição

Descrição geral

RAD51 (RAD51 recombinase) belongs to the RecA/RadA/Rad51 protein family. It has a conserved ATP binding core. This protein is expressed in testis, ovary, and lymphoid tissue. It is located on human chromosome 15q15.

Imunogênio

The antiserum was produced against synthesized peptide derived from human RAD51 around the phosphorylation site of Tyr315.

Immunogen Range: 281-330

Aplicação

Anti-phospho-RAD51 (pTyr315) antibody has been used in western blotting.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Ações bioquímicas/fisiológicas

RAD51 (RAD51 recombinase) plays a major role in homology-directed repair (HDR) and cell viability.This gene acts an an important target for cancer therapy. RAD51 interacts with BRCA2 (breast cancer susceptibility protein) and participates in DSB (double strand DNA breaks) repair.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable