SAB4300637

Anti-FGFR4 antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-CD334, Anti-JTK2, Anti-MGC20292, Anti-TKF
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: ~110 kDa
• reatividade de espécies: human, rat
• concentração: 1 mg/mL
• técnica(s): western blot: 1:500-1:1000
• Isotipo: IgG
• sequência de imunogênio: (L-T-V-A-L)
• nº de adesão NCBI: NM_002011.3
• nº de adesão UniProt: P22455
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... FGFR4(2264)

Descrição

Descrição geral

FGFR4 (fibroblast growth factor receptor 4) belongs to FGFR kinase family. In adult tissues, FGFR is expressed in a cell type-specific mode. It is located on chromosome 5q35.

The antibody detects endogenous level of total FGFR4 protein.

Imunogênio

Peptide sequence around aa. 45-49 ( L-T-V-A-L), according to the protein NP_002002.3

Ações bioquímicas/fisiológicas

Aberrations in FGFR4 results in neuroblastoma and altered receptor degradation. It acts as a predictive biomarker in oral and oropharyngeal squamous cell carcinoma. Suppressing FGFR4 may affect the biological characteristics in gastric cancer cells.

Características e benefícios

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Descrição-alvo

Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.

forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable