SAB4200827

Anti- Staphylococcal alpha-Toxin-Peroxidase antibody produced in rabbit

IgG fraction of antiserum

• Sinônimo(s): Alpha-hemolysin (hly)
• Código UNSPSC: 12352203

Propriedades

• conjugado: peroxidase conjugate
• forma do anticorpo: IgG fraction of antiserum
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• descrição: Research area: Microbiome
• Formulário: lyophilized powder
• peso molecular: ~33 kDa
• reatividade de espécies: Staphylococcus aureus (alpha-Toxin (a-Hemolysin) )
• concentração: ~4 mg/mL
• técnica(s): direct ELISA: 1:2,000-1:4,000 using 1 μg/mL Staphylococcal alpha-Toxin (a-Hemolysin) for coating.
• nº de adesão UniProt: P09616
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: Staphylococcus aureus subsp. aureus NCTC 8325 ... SAOUHSC_01121(3920722)

Descrição

Descrição geral

Staphylococcal alpha-Toxin is a pore forming cytotoxin. Native alpha toxin is a water-soluble monomer but later on gets converted to β-barrel in the host membranes. It is 34 kDa protein. The N- terminal and the C-terminal are involved in forming a membrane-binding epitope and the central domain forms a membrane-inserting, pore forming domain.

Especificidade

Anti-Staphylococcal alpha-Toxin-peroxidase antibody specifically recognizes Staphylococcal alpha-Toxin (?-Hemolysin) and has no cross reactivity with Staphylococcal Enterotoxin A (SEA), Cholera Toxin or Pseudomonas Exotoxin A

Imunogênio

purified toxin from Staphylococcus aureus

Aplicação

The antibody may be used in various immunochemical techniques including ELISA

Ações bioquímicas/fisiológicas

Staphylococcal alpha-Toxin plays a role in binding to the host membrane. At higher concentrations it makes the cells which are devoid of receptors to become more permeable and hence also to protein-free lipid bilayers.

Implicações do diagnóstico

Unless otherwise stated in our catalog  our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

forma física

Supplied as a lyophilized powder.

Armazenamento e estabilidade

Store the lyophilized product at 2–8 °C. For extended storage after reconstitution, keep at –20 °C in working aliquots. Avoid repeated freeze-thaw cycles. For continuous use after reconstitution, keep at 2–8 °C for up to 1 month. Solutions at working dilution should be discarded if not used within 12 hours.

Exoneração de responsabilidade

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable