SAB4100599

Anti-KRAS Antibody

mouse monoclonal, KRAS-A582

• Sinônimo(s): Anti-C-K-RAS, Anti-K-RAS2A, Anti-K-RAS2B, Anti-K-RAS4A, Anti-K-RAS4B
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• Nome do produto: Anti-KRAS antibody, Mouse monoclonal, clone KRAS-A582, purified from hybridoma cell culture
• fonte biológica: mouse
• Nível de qualidade: 200
• conjugado: unconjugated
• forma do anticorpo: purified from hybridoma cell culture
• tipo de produto de anticorpo: primary antibodies
• clone: KRAS-A582, monoclonal
• Formulário: aqueous solution
• peso molecular: antigen predicted mol wt 27.9 kDa
• reatividade de espécies: human
• técnica(s): western blot: suitable using 5-10ug/ml using HEK-293 cells expressing KRAS
• Isotipo: IgG1
• nº de adesão UniProt: P01116
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... KRAS(3845)

Descrição

Descrição geral

The kirsten rat sarcoma-2 virus oncogene (KRAS) gene is mapped to human chromosome 12p12.1 and belongs to the family of Ras genes. The protein encoded is a small guanosine nucleotide-bound GTPases belonging.

Imunogênio

KRAS purified recombinant protein

Ações bioquímicas/fisiológicas

Mutation in the KRAS gene causes non small-cell lung cancer and promotes tumor initiation, progression and metastasis. Altered KRAS gene also offers resistance to chemotherapy. It is involved in the signal transduction between epidermal growth factor receptor (EGFR) to the nucleus.

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable