SAB3500514

Anti-ZEB1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): Anti-AREB6, Anti-BZP, Anti-TCF8, Anti-Zinc finger E-box binding homeobox 1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: predicted mol wt 124 kDa
• reatividade de espécies: human
• técnica(s): immunocytochemistry: suitable; immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• nº de adesão NCBI: CAI12550
• nº de adesão UniProt: P37275
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... ZEB1(6935)

Descrição

Descrição geral

Zinc finger E-box-binding homeobox 1 (ZEB1) is an EMT (epithelial-mesenchymal transition) transcription factor. The gene encoding this protein is localized on human chromosome 10p11.2.

Imunogênio

ZEB1 antibody was raised against a 15 amino acid peptide near the center of human ZEB1.

The immunogen is located within amino acids 530 - 580 of ZEB1.

Aplicação

Anti-ZEB1 antibody produced in rabbit has been used in western blotting.

Ações bioquímicas/fisiológicas

Zinc finger E-box-binding homeobox 1 (ZEB1) controls the expression of E-cadherin as a repressor. It plays an important role in tumor invasion and metastasis. Epigenetic suppression of ZEB1 might be a useful tool for overcoming drug resistance in human breast cancer. Mutations in this gene are associated with posterior polymorphous corneal dystrophy and Fuchs′ endothelial corneal dystrophy (FECD6).

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Ligação

The action of this antibody can be blocked using blocking peptide SBP3500514.

forma física

Supplied in PBS with 0.02% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable