SAB1104559
Anti-NUPR1 (47-60) antibody produced in rabbit
IgG fraction of antiserum
Sinônimo(s):
Anti-COM1, Anti-Nuclear protein, transcriptional regulator, 1
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
Produtos recomendados
fonte biológica
rabbit
conjugado
unconjugated
forma do anticorpo
IgG fraction of antiserum
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
Formulário
buffered aqueous solution
peso molecular
antigen predicted mol wt ~9 kDa
reatividade de espécies
human
técnica(s)
western blot: 1:500-1:2,000
nº de adesão UniProt
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... NUPR1(26471)
Descrição geral
The NUPR1 (nuclear protein 1, transcriptional regulator) gene is mapped to human chromosome 16p11.2 and encodes a chromatin remodeling protein of 8.8 KDa.
Imunogênio
synthetic peptide corresponding to amino acids 47-60 of human NUPR1
Aplicação
Anti-NUPR1 (47-60) antibody produced in rabbit has been used in western blot analysis.
Ações bioquímicas/fisiológicas
Nupr1 (nuclear protein 1, transcriptional regulator) is a stress response factor, induced by lipopolysaccharides, CCl4, starvation, cell cycle arrest and other protein stimuli. NUPR1 is associated with tumor cell proliferation, metastasis and apoptosis, also regulates entosis, matrix remodeling and autophagy. It serves as a substrate for protein kinase A. Overexpression of this gene is observed in glioblastoma and hepatocellular carcinoma. The protein function is tissue specific and differs at molecular level. It can act as a tumor suppressor or inducer.
forma física
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Priscila R Andrade et al.
PLoS neglected tropical diseases, 13(7), e0007589-e0007589 (2019-07-26)
The initial interaction between a microbial pathogen and the host immune response influences the outcome of the battle between the host and the foreign invader. Leprosy, caused by the obligate intracellular pathogen Mycobacterium leprae, provides a model to study relevant
A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.
Maida A, et al.
The Journal of Clinical Investigation, 126(9), 3263-3278 (2016)
Pivotal role of the chromatin protein Nupr1 in Kras-induced senescence and transformation.
Grasso D, et al.
Scientific Reports, 5, 17549-17549 (2015)
NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance.
Emma M R, et al.
Cell Death & Disease, 7(6), e2269-e2269 (2016)
A new microRNA signal pathway regulated by long noncoding RNA TGFB2-OT1 in autophagy and inflammation of vascular endothelial cells.
Huang S, et al.
Autophagy, 11(12), 2172-2183 (2015)
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