P7556

Progesterone-Water Soluble

powder, BioReagent, suitable for cell culture

• Sinônimo(s): Progesterone: HBC complex, Progesterone: methyl-β-cyclodextrin complex
• Número MDL: MFCD00003658
• Código UNSPSC: 12352209
• ID de substância PubChem: 57654558
• NACRES: NA.77

Propriedades

• fonte biológica: synthetic (organic)
• linha de produto: BioReagent
• forma: powder
• concentração: ≥65% (HPLC)
• técnica(s): cell culture | mammalian: suitable
• solubilidade: H₂O: 25 mg/mL, clear to slightly hazy
• Condições de expedição: ambient
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(C)=O
• InChI: 1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
• chave InChI: RJKFOVLPORLFTN-LEKSSAKUSA-N
• Informações sobre genes: human ... ABCB1(5243) , AR(367) , CYP2C9(1559) , EBP(10682) , ESR1(2099) , ESR2(2100) , NR3C1(2908) , NR3C2(4306) , PGR(5241) , SERPINA6(866) ; mouse ... Esr1(13982) ; rat ... Ar(24208) , Nr3c1(24413) , Pgr(25154)

Descrição

Descrição geral

Progesterone is a steroid hormone secreted by the ovaries.

Aplicação

Progesterone-Water Soluble has been used:

• for in vitro maturation of oocyte complexes
• as a σ1R antagonist to study its effect on sigma 1 receptor
• to study its effect on the differentiation of human multipotent mesenchymal stromal cells (hMSCs) in vitro

This product is not recommended for use in binding assays.

Ações bioquímicas/fisiológicas

Progesterone is a hormone that maintains pregnancy. It is essential for embryo formation, development and survival in almost all mammals. This hormone exhibits its action via progesterone receptor, which is specifically expressed in the endometrial stroma throughout pregnancy. It is known to prevent preterm delivery, when administered intramuscularly. Progesterone also controls gonadotropin secretion, activates sexual behavior and triggers ovarian events leading to ovulation. It stimulates the growth and differentiation of the uterus and prevents uterine contractility.

Embalagem

Package size based on progesterone content

Outras notas

Contains approx. 70 mg progesterone per gram; balance methyl-β-cyclodextrin.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Danger
• Frases de perigo: H351,H360FD,H362
• Declarações de precaução: P202 - P260 - P263 - P264 - P280 - P308 + P313
• Classificações de perigo: Carc. 2 - Lact. - Repr. 1A
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable