P3591
1,2-Dioctanoyl-sn-glycerol 3-phosphate sodium salt
≥99%
Sinônimo(s):
L-α-Phosphatidic acid, dioctanoyl sodium salt
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About This Item
Fórmula linear:
C19H36O8PNa
Número CAS:
Peso molecular:
446.45
Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.77
Produtos recomendados
Ensaio
≥99%
Formulário
powder
temperatura de armazenamento
−20°C
InChI
1S/C19H37O8P.Na/c1-3-5-7-9-11-13-18(20)25-15-17(16-26-28(22,23)24)27-19(21)14-12-10-8-6-4-2;/h17H,3-16H2,1-2H3,(H2,22,23,24);/q;+1/p-1/t17-;/m1./s1
chave InChI
ZNDNSOYDPUTHKQ-UNTBIKODSA-M
Descrição geral
1,2-Dioctanoyl-sn-glycerol 3-phosphate sodium salt is a cell-permeable phosphatidic acid (PA).[1]
Aplicação
1,2-Dioctanoyl-sn-glycerol 3-phosphate sodium salt has been used:
- to study its effects on neural stem/precursor cell (NSC) proliferation[2]
- to study the effects of phosphatidic acid (PA) on actin filament dynamics in Arabidopsis thaliana epidermal leaf cells[3]
- to treat vector-transfected cells and to verify the attenuation of hypoxia-inducible factor-1α (HIF-1α) induction in phospholipase D (PLD)-transfected cells by butanol[1]
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acid
Han S, et al.
Experimental & Molecular Medicine, 46(12), e126-e126 (2014)
ETOH inhibits embryonic neural stem/precursor cell proliferation via PLD signaling
Fujita Y, et al.
Biochemical and Biophysical Research Communications, 370(1), 169-173 (2008)
Yuko Fujita et al.
Biochemical and biophysical research communications, 370(1), 169-173 (2008-03-25)
While a mother's excessive alcohol consumption during pregnancy is known to have adverse effects on fetal neural development, little is known about the underlying mechanism of these effects. In order to investigate these mechanisms, we investigated the toxic effect of
Jindřiška Matoušková et al.
Plant science : an international journal of experimental plant biology, 223, 36-44 (2014-04-29)
Changes in actin cytoskeleton dynamics are one of the crucial players in many physiological as well as non-physiological processes in plant cells. Positioning of actin filament arrays is necessary for successful establishment of primary lines of defense toward pathogen attack
Songyi Han et al.
Experimental & molecular medicine, 46, e126-e126 (2014-12-20)
Growth factor-stimulated phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine (PC), generating phosphatidic acid (PA) which may act as a second messenger during cell proliferation and survival. Therefore, PLD is believed to play an important role in tumorigenesis. In this
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