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P169

Supelco

Protriptyline hydrochloride

Sinônimo(s):

N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine hydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C19H21N · HCl
Número CAS:
1225-55-4
Peso molecular:
299.84
Número CE:
214-956-3
Número MDL:
MFCD00072057
Código UNSPSC:
41116107

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

formato

neat

cadeia de caracteres SMILES

Cl[H].CNCCCC1c2ccccc2C=Cc3ccccc13

InChI

1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3;1H

chave InChI

OGQDIIKRQRZXJH-UHFFFAOYSA-N

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Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

substituído por

Nº do produto
Descrição
Preços

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Nonsurgical management of the obstructive sleep apnea patient.
W K Thornton et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 54(9), 1103-1108 (1996-09-01)
K E Kinnamon et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 216(3), 424-428 (1997-12-24)
Forty-nine "standard" compounds known to be useful in the treatment of other diseases were tested for their suppressive activity against the trypomastigotes of Trypanosoma cruzi-infected mice. The most active was the antidepressant protriptyline, which was almost three times as effective
Y Huang
British journal of pharmacology, 117(3), 533-539 (1996-02-01)
1 The effects of noradrenaline (NA) uptake inhibitors on contractions induced by NA, high K+, and 12-O-tetradecanoylphorbol-13-acetate (TPA) in rat isolated aorta were investigated. 2 Protriptyline (0.3 microM) and amitriptyline (0.3 microM) produced an approximately parallel shift to the right
J R Wooltorton et al.
British journal of pharmacology, 116(4), 2191-2200 (1995-10-01)
1. The block of K+ currents by amitriptyline and the related tricyclic compounds cyproheptadine and dizocilpine was studied in dissociated rat sympathetic neurones by whole-cell voltage-clamp recording. 2. Cyproheptadine (30 microM) inhibited the delayed-rectifier current (Kv) by 92% and the
B T Duhart et al.
Xenobiotica; the fate of foreign compounds in biological systems, 29(7), 733-746 (1999-08-24)
1. The potential of various fungi to metabolize protriptyline (an extensively used antidepressant) was studied to investigate similarities between mammalian and microbial metabolism. 2. Metabolites produced by each organism were isolated by high-pressure liquid chromatography and identified by nuclear magnetic
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