O2756

Oxytetracycline hemicalcium salt

• Fórmula linear: C₂₂H₂₄N₂O₉ · 1/2Ca
• Número CAS: 15251-48-6
• Peso molecular: 480.47
• Número CE: 239-293-7
• Número MDL: MFCD00151362
• Código UNSPSC: 51101500
• ID de substância PubChem: 24897968

Propriedades

• solubilidade: formic acid: 50 mg/mL, very slightly hazy, orange to very deep orange
• espectro de atividade do antibiótico: Gram-negative bacteria; Gram-positive bacteria
• Modo de ação: protein synthesis | interferes
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [Ca++].CN(C)[C@H]1[C@@H]2[C@@H](O)C3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1[O-])C(=O)c4c(O)cccc4[C@@]3(C)O.CN(C)[C@H]5[C@@H]6[C@@H](O)C7C(=C(O)[C@]6(O)C(=O)C(C(N)=O)=C5[O-])C(=O)c8c(O)cccc8[C@@]7(C)O
• InChI: 1S/2C22H24N2O9.Ca/c2*1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h2*4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);/q;;+2/p-2/t2*12?,13-,14+,17+,21-,22+;/m11./s1
• chave InChI: KIPLYOUQVMMOHB-JOFVZRTQSA-L

Descrição

Descrição geral

Chemical structure: tetracycline

Aplicação

Oxytetracycline is a tetracycline analog isolated from the actinomycete Streptomyces rimosus. Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). It is used for fluorescence measurements of hepatocytes.

Ações bioquímicas/fisiológicas

Oxytetracycline inhibits translation which results in cell death. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic so it can easily pass through a cell membrane and passively diffuses through channels in the bacterial membrane.

Outras notas

Keep container tightly closed in a dry and well-ventilated place.

Informações de segurança

• Pictogramas: GHS08,GHS09
• Palavra indicadora: Warning
• Frases de perigo: H361d,H411
• Declarações de precaução: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Classificações de perigo: Aquatic Chronic 2 - Repr. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)