N9407
Neuropeptide Y Fragment 3-36 human, rat
≥95% (HPLC)
Sinônimo(s):
NPY 3-36
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250 μG
R$ 1.939,00
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250 μG
R$ 1.939,00
About This Item
Fórmula empírica (Notação de Hill):
C175H269N53O54S
Número CAS:
Peso molecular:
4011.40
Número MDL:
Código UNSPSC:
51111800
NACRES:
NA.32
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Amino Acid Sequence
Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
Descrição geral
Neuropeptide Y (NPY) is a regulatory protein consisting of 36 amino acids. It is ubiquitously expressed in the heart and brain. NPY is a member of pancreatic polypeptide family. The gene encoding this protein is localized on human chromosome 7p15.[1]
Ações bioquímicas/fisiológicas
Endogenous neuropeptide that selectively binds to Y<SUB>2</SUB> and Y<SUB>5</SUB> receptors.
Neuropeptide Y (NPY) plays a vital role in various processes like feeding behavior, anxiety, epilepsy, circadian rhythm, sleep, pain and drug addiction. It also modulates appetite, body weight and obesity. The protein has potent vasoactive effects on the cardiovascular system and controls central endocrine secretion. NPY is involved in the pathogenesis of atherosclerosis and coronary artery disease.[1][2]
Neuropeptide Y (NPY) plays a vital role in various processes like feeding behavior, anxiety, epilepsy, circadian rhythm, sleep, pain and drug addiction. It also modulates appetite, body weight and obesity. The protein has potent vasoactive effects on the cardiovascular system and controls central endocrine secretion. NPY is involved in the pathogenesis of atherosclerosis and coronary artery disease.[1][2]
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Eitezaz Mahmood et al.
European journal of pharmacology, 882, 173261-173261 (2020-06-14)
Neuropeptide-Y (NPY) leads to angiogenesis and remodeling of the ischemic myocardium. The objective of this study is to assess the therapeutic potential of NPY in a model of acute myocardial ischemia using a nanoparticles delivery system targeted to tissue with
Genetic studies of neuropeptide Y and neuropeptide Y receptors Y1 and Y5 regions in morbid obesity
C Roche
Diabetologia, 40, 671?675-671?675 (1997)
R Mentlein et al.
Regulatory peptides, 49(2), 133-144 (1993-12-10)
Neuropeptide Y, peptide YY and pancreatic polypeptide share an evolutionary conserved proline-rich N-terminal sequence, a structure generally known to be inert to the attack of common proteinases, but a potential target for specialized proline-specific aminopeptidases. Purified human dipeptidyl peptidase IV
K N Browning et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 12(1), 33-41 (2000-01-29)
Intracellular recordings were made from myenteric neurones of the guinea-pig descending colon. Neuropeptide Y (NPY) and related pancreatic polypeptides were applied by superfusion and the effects upon the amplitude of fast excitatory synaptic potentials (ESPs) and the ratio of paired
D Grandt et al.
Regulatory peptides, 67(1), 33-37 (1996-11-14)
Neuropeptide Y (NPY 1-36) binds to Y1 and Y2 receptors with similar affinity. No endogenous molecular form of NPY with selectivity for Y1 or Y2 receptors has been described so far. We report the presence of an endogenous fragment of
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