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MAK077

Sigma-Aldrich

Uric Acid Assay Kit

sufficient for 100 colorimetric or fluorometric tests

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About This Item

Código UNSPSC:
12161503
NACRES:
NA.84

uso

sufficient for 100 colorimetric or fluorometric tests

método de detecção

colorimetric
fluorometric

doença(s) relevante(s)

endocrinological disorders, diabetes; cardiovascular diseases; rheumatological diseases; genitourinary disorders

temperatura de armazenamento

−20°C

Descrição geral

In humans and primates, uric acid is the end product of purine metabolism. It is produced by the oxidation of xanthine and hypoxanthine by xanthine oxidase and excreted in urine. High serum levels of uric acid, hyperuricemia, are associated with insulin resistance, cardiovascular disease, and gout. The mechanisms leading to hyperuricemia are typically either increased uric acid production or decreased urine excretion. Increased serum uric acid may be a marker of renal disease[1].

Aplicação

Uric Acid Assay Kit has been used
  • to determine the uric acid content in human adipose-derived stem cell culture supernatant[2]
  • to measure serum uric acid level in order to analyse kidney function in rat models[3]
  • to determine the uric acid concentration in serum and to study the e antiinflammatory effects of sunflower head ethanol extract in rats[4]
  • in quantitative analysis of uric acid degradation[5]

Adequação

Suitable for detecting uric acid in biological samples such as serum and urine. Pretreatment of samples is not required

Princípio

In this assay, Uric Acid concentration is determined by a coupled enzyme reaction, which results in a colorimetric (570 nm)/fluorometric (λex = 535/λem = 587 nm) product, proportional to the Uric Acid present.

produto relacionado

Nº do produto
Descrição
Preços

Pictogramas

Health hazard
GHS08

Palavra indicadora

Danger

Frases de perigo

H334,H412

Declarações de precaução

P261 - P273 - P284 - P501

Classificações de perigo

Aquatic Chronic 3 - Resp. Sens. 1

Código de classe de armazenamento

10 - Combustible liquids

Ponto de fulgor (°F)

188.6 °F - closed cup

Ponto de fulgor (°C)

87 °C - closed cup

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Certificados de análise (COA)

Lot/Batch Number
7M29K06080
8E04K06080
7G12K06080
7B22K06080
6E29K06080

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Effect of humic substances on rumen fermentation, nutrient digestibility, methane emissions, and rumen microbiota in beef heifers.
Terry S A, et al.
Journal of Animal Science (2018)
Gabriel O Ribeiro et al.
Scientific reports, 7(1), 1276-1276 (2017-04-30)
Future growth in demand for meat and milk, and the socioeconomic and environmental challenges that farmers face, represent a "grand challenge for humanity". Improving the digestibility of crop residues such as straw could enhance the sustainability of ruminant production systems.
Stephanie A Terry et al.
Journal of animal science, 96(9), 3863-3877 (2018-09-01)
Ruminants play an important role in food security, but there is a growing concern about the impact of cattle on the environment, particularly regarding greenhouse gas emissions. The objective of this study was to examine the effect of humic substances
A Role for Uric Acid in the Progression of Renal Disease.
Kang, D.-H
Journal of the American Society of Nephrology, 12, 2888-2897 (2002)
Stephanie A Terry et al.
Frontiers in veterinary science, 6, 308-308 (2019-10-15)
The objective of this study was to examine the effect of a pine enhanced biochar (EB) on rumen fermentation, apparent total tract digestibility, methane (CH4) emissions, and the rumen and fecal microbiome of Angus × Hereford heifers fed a barley
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Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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