The solubility of this product is tested in chloroform at 50 mg/mL. Solution stability has not been determined, however the acetate form is unstable in solution and should be prepared fresh. The end user would have to validate solution stability of this compound experimentally. The NIH lists the material as being soluble in ethanol, methanol, ether, and acetone. Please see the link below to review this publication:
https://pubchem.ncbi.nlm.nih.gov/compound/Medroxyprogesterone#section=Color-Form
M6013
Medroxyprogesterone
Sinônimo(s):
17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione, 17α-Hydroxy-6α-methylprogesterone, 6α-Methyl-5-pregnen-17α-ol-3,20-dione, 6-Dihydromegestrol
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About This Item
Fórmula empírica (Notação de Hill):
C22H32O3
Número CAS:
Peso molecular:
344.49
Beilstein:
2510965
Número CE:
Número MDL:
Código UNSPSC:
51111800
ID de substância PubChem:
NACRES:
NA.77
Preço e disponibilidade não estão disponíveis no momento.
Produtos recomendados
fonte biológica
synthetic (organic)
Nível de qualidade
Ensaio
≥98% (HPLC)
Formulário
powder
solubilidade
chloroform: 50 mg/mL, clear, colorless to faintly yellow
Condições de expedição
ambient
temperatura de armazenamento
room temp
cadeia de caracteres SMILES
[H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(C)=O
InChI
1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1
chave InChI
FRQMUZJSZHZSGN-HBNHAYAOSA-N
Informações sobre genes
rat ... Ar(24208)
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Atenção
Much of the pharmacology literature refers to medroxyprogesterone acetate as medroxyprogesterone, but they are of course not the same substance.
produto relacionado
Nº do produto
Descrição
Preços
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Repr. 2
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Equipamento de proteção individual
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Adarsh J Sai et al.
Menopause (New York, N.Y.), 18(10), 1101-1112 (2011-06-30)
The aim of this study was to examine the effect of conjugated equine estrogens alone (ET), conjugated equine estrogens + medroxyprogesterone (EPT), calcitriol alone, calcitriol + EPT/ET, or placebo on serum lipid profile and analyze the interaction with estrogen receptor-α
M F Fung et al.
Obstetrics and gynecology, 78(6), 1033-1038 (1991-12-01)
We conducted a retrospective review of 44 patients with metastatic or recurrent endometrial carcinoma treated with cisplatin, doxorubicin, cyclophosphamide, and medroxyprogesterone acetate. Thirty-six women had metastatic disease; eight had recurrent disease. In the metastatic group, 12 women had positive peritoneal
Clinical significance of differences in bioavailability of medroxyprogesterone acetate preparations.
A D Stockdale et al.
Clinical pharmacokinetics, 16(3), 129-133 (1989-03-01)
Carolyn J Crandall et al.
Breast cancer research and treatment, 132(1), 275-285 (2011-11-02)
The associations between breast tenderness during use of conjugated equine estrogen (CEE) therapy with or without medroxyprogesterone (MPA) therapy and subsequent breast cancer risk are unknown. We analyzed data from the Women's Health Initiative Estrogen plus Progestin (N = 16,608
M F Martinez et al.
Reproduction in domestic animals = Zuchthygiene, 47(2), 230-237 (2011-09-03)
Two experiments were designed to investigate the administration of intravaginal progesterone in protocols for oestrus and ovulation synchronization in beef heifers. In Experiment 1, cyclic Black Angus heifers (n = 20) received an Ovsynch protocol and were randomly assigned to
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is there is any other solution can be used to dissolve the Medroxyprogesterone and whats the tempreture we need to use for stoarge after dissolving the Medroxyprogesterone
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