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M5634

Sigma-Aldrich

5-Mercuricytidine carbonate 5′-triphosphate triethylammonium salt

~90%

Sinônimo(s):

Hg-CTP

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About This Item

Fórmula linear:
C9H15HgN3O14P3 · HCO3
Número CAS:
100940-62-3
Peso molecular:
1148.52
Número MDL:
MFCD00058366
Código UNSPSC:
41106305
ID de substância PubChem:
329818019
NACRES:
NA.51

Ensaio

~90%

Formulário

solid

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CCN(CC)CC.NC1=NC(=O)N(C=C1[Hg])[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O

InChI

1S/C9H15N3O14P3.C6H15N.Hg/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;1-4-7(5-2)6-3;/h2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);4-6H2,1-3H3;/t4-,6-,7-,8-;;/m1../s1

chave InChI

CKMVNPSLWQKVPG-WFIJOQBCSA-N

Aplicação

5-Mercuricytidine carbonate 5;-triphosphate (Hg-CTP) may be used as a substrate to generate mercurated DNA that may be suitable for image based DNA sequencing strategies.

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Lot/Batch Number

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A J Bridgman et al.
DNA sequence : the journal of DNA sequencing and mapping, 6(4), 199-209 (1996-01-01)
The development of high-resolution scanning-probe microscopes has reawakened interest in the possibility of sequencing large nucleic acid molecules by direct imaging. Such an approach would be facilitated by the availability of effective methods for increasing contrast by labelling specific nucleotides
Study of deoxyribonucleic acid replication in permeable cells of Bacillus subtilis using mercurated nucleotide substrates.
S Bhattacharya et al.
Biochemistry, 20(11), 3029-3034 (1981-05-26)
Structural analyses on the mercury(II)-mediated T-T base pair.
Tanaka Y, Oda S, et al.
Nucleic Acids Symposium Series, 50, 47-48 (2006)
R M Dale et al.
Proceedings of the National Academy of Sciences of the United States of America, 70(8), 2238-2242 (1973-08-01)
A simple acetoxymercuration reaction for introducing covalently bound mercury atoms into nucleotides is described. The 5-mercuriacetate derivatives of UTP, CTP, dUTP, and dCTP, as well as the 7-mercuriacetate derivative of 7-deazaATP, have been prepared by this procedure and tested as
S Bhattacharya et al.
The Journal of biological chemistry, 257(4), 1610-1612 (1982-02-25)
Mercurated DNA was synthesized in permeable cells of Bacillus subtilis, using 5-mercurideoxycytidine triphosphate as one of the substrates, and was separated from parental unsubstituted DNA by isopycnic centrifugation in CsCl gradients. The ability of mercurated DNA to transform auxotrophic strains
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