M2521
IgM, Lambda from murine myeloma
clone MOPC 104E, ascites fluid, lyophilized powder
Sinônimo(s):
Mouse IgM-λ
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About This Item
Produtos recomendados
fonte biológica
mouse
Nível de qualidade
conjugado
unconjugated
forma do anticorpo
ascites fluid
clone
MOPC 104E, monoclonal
forma
lyophilized powder
temperatura de armazenamento
2-8°C
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Descrição geral
The MOPC-104E tumor line that produces mouse IgM is a mineral oil induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. IgM is present on the surface of B lymphocytes in its monomeric form.
Especificidade
Antigen Specificity: α(1→3) glucose
Aplicação
IgM, λ from murine myeloma has been used as control in chromatin immunoprecipitation analysis. It has also been used in immunohistochemitsry.
IgM, λ from murine myeloma was used as a control antibody in ChIP analysis of GATA-1-null and GATA-1-positive G1E cells.
Ações bioquímicas/fisiológicas
IgM antibodies are present as pentamers in the serum and are produced in response to antigens.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
Certificados de análise (COA)
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GATA-1-mediated Transcriptional Repression Yields Persistent Transcription Factor IIB-Chromatin Complexes
Martowicz ML, et al.
The Journal of biological chemistry, 281(49), 37345-37352 (2006)
D Chen et al.
The American journal of physiology, 277(3), H1100-H1106 (1999-09-14)
Abnormal proliferation of vascular smooth muscle cells (VSMCs) is thought to play an important role in the pathogenesis of atherosclerosis and restenosis. Previous studies have implicated the extracellular matrix protein thrombospondin-1 (TSP1) in mitogen-dependent proliferation of VSMCs. In this study
Molecular Genetics of Immunoglobulin, 17 (1987)
The Immunoglobulins: Structure and Function (1998)
Melissa L Martowicz et al.
The Journal of biological chemistry, 281(49), 37345-37352 (2006-09-12)
The hematopoietic GATA factors GATA-1 and GATA-2, which have distinct and overlapping roles to regulate blood cell development, are reciprocally expressed during erythropoiesis. GATA-1 directly represses Gata2 transcription, and reduced GATA-2 synthesis promotes red blood cell development. Gata2 repression involves
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