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M0763

Sigma-Aldrich

Metoclopramide hydrochloride

Metoclopramide hydrochloride

solid

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10 G
R$ 733,00
25 G
R$ 1.274,00
100 G
R$ 3.453,00

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10 G
R$ 733,00
25 G
R$ 1.274,00
100 G
R$ 3.453,00

About This Item

Fórmula empírica (Notação de Hill):
C14H22ClN3O2 · HCl
Número CAS:
7232-21-5
Peso molecular:
336.26
Número CE:
230-634-5
Número MDL:
MFCD00058011
Código UNSPSC:
12352200
ID de substância PubChem:
24277919
NACRES:
NA.77

R$ 733,00

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Formulário

solid

cor

white

solubilidade

H2O: soluble

originador

Baxter

cadeia de caracteres SMILES

Cl.CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC

InChI

1S/C14H22ClN3O2.ClH/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3;/h8-9H,4-7,16H2,1-3H3,(H,17,19);1H

chave InChI

RVFUNJWWXKCWNS-UHFFFAOYSA-N

Informações sobre genes

human ... DRD2(1813) , HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242) , HTR4(3360)

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Ações bioquímicas/fisiológicas

D2 antagonist; 5-HT3 antagonist; antipsychotic; anti-emetic.

Características e benefícios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Baxter. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302

Declarações de precaução

P264 - P270 - P301 + P312 - P501

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
MKCW1033
MKCV1506
MKCR7208
MKCQ4308
MKCL8990

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B Y De Winter et al.
Gut, 45(5), 713-718 (1999-10-13)
The effects of different prokinetic agents, the motilide erythromycin and the substituted benzamides metoclopramide and cisapride, were investigated in a rat model of postoperative ileus. These effects were compared with that of granisetron, a 5-hydroxytryptamine (5-HT(3)) receptor antagonist, and a
Diogo F Antunes et al.
Molecular and cellular endocrinology, 550, 111649-111649 (2022-04-19)
Dopamine is part of the reward system triggering the social decision-making network in the brain. It has hence great potential importance in the regulation of social behaviour, but its significance in the control of behaviour in highly social animals is
M K Ladola et al.
Indian journal of pharmaceutical sciences, 76(5), 423-429 (2014-11-27)
In the present investigation, a novel multifunctional co-processed superdisintegrants consisting of crospovidone and Kyron T-314 were fabricated by solvent evaporation method to develop melt-in-mouth tablets of metoclopramide hydrochloride with a view to enhance patient compliance by direct compression method. The
R W Pero et al.
Molecular and cellular biochemistry, 193(1-2), 119-125 (1999-05-20)
Our laboratory has concentrated on the possible regulation the benzamides and nicotinamides may have on the processes of DNA repair and apoptosis. Recent reports have suggested that both apoptosis and inflammation are regulated by the transcription factor NF-kappaB. We have
Mark L Kovler et al.
Science translational medicine, 13(612), eabg3459-eabg3459 (2021-09-23)
Necrotizing enterocolitis (NEC) is a devastating disease of premature infants, whose pathogenesis remains incompletely understood, although activation of the Gram-negative bacterial receptor Toll-like receptor 4 (TLR4) on the intestinal epithelium plays a critical role. Patients with NEC typically display gastrointestinal
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