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L9895

Sigma-Aldrich

Lectin from Pseudomonas aeruginosa

lyophilized powder

Sinônimo(s):

PA-I

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About This Item

Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.32

forma

lyophilized powder

Nível de qualidade

potência

<15 μg/mL per mL agglutination activity

temperatura de armazenamento

−20°C

Ações bioquímicas/fisiológicas

PA-I has a major affinity for D-galactose and its derivatives. PA-I agglutinates all types of human and animal erythrocytes and interacts also with unicellular protozoa, algae and bacteria. PA-I induces mitogenic stimulation in cultured human lymphocytes pretreated with neuraminidase.

Embalagem

Package size based on protein content. Vial content based on protein by biuret.

Qualidade

Highly purified.

forma física

Lyophilized powder containing approx. 80% protein (biuret), balance primarily sodium citrate, plus traces of calcium chloride, magnesium chloride and manganese chloride

Nota de preparo

Purified by affinity chromatography using a modification of Gilboa-Garber.1

Nota de análise

Agglutination activity is expressed in μg/ml and is determined from serial dilutions of a 1 mg/ml solution using phosphate buffered saline, pH 7.0. This activity is the lowest concentration to agglutinate a 2% suspension of neuraminidase treated human blood group A erythrocytes after one hr incubation at 25 °C.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


Certificados de análise (COA)

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Alessandro Palmioli et al.
Chembiochem : a European journal of chemical biology, 20(23), 2911-2915 (2019-06-20)
Biofilm formation by bacterial pathogens is a hallmark of chronic infections and is associated to increased antibiotic tolerance that makes pathogens difficult to eradicate with conventional antibiotic therapies. Infections caused by Pseudomonas aeruginosa are of great concern, especially for immunocompromised
Akiko Chiba et al.
Molecular cancer research : MCR, 18(1), 130-139 (2019-10-20)
Breast tumors have their own specific microbiota, distinct from normal mammary gland tissue. Patients with breast cancer that present with locally advanced disease often undergo neoadjuvant chemotherapy to reduce tumor size prior to surgery to allow breast conservation or limit

Artigos

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