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L3262

Sigma-Aldrich

Anti-Lactoferrin antibody produced in rabbit

fractionated antiserum, lyophilized powder

Sinônimo(s):

Anti-Draculin, Anti-Draculin-1

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About This Item

Número MDL:
MFCD00162524
Código UNSPSC:
12352203
NACRES:
NA.46

fonte biológica

rabbit

Nível de qualidade

200

conjugado

unconjugated

forma do anticorpo

fractionated antiserum

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

lyophilized powder

reatividade de espécies

human

embalagem

vial of 2 mL lyophilized antiserum

técnica(s)

direct ELISA: 1:10,000 using using human lactoferrin

nº de adesão UniProt

P02788

temperatura de armazenamento

2-8°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... LTF(4057)

Categorias relacionadas

Descrição geral

Lactoferrin, globular glycoprotein belongs to transferrin protein family. It is mapped to human chromosome 3p21.31. Lactoferrin comprises 692 amino acids with two globular lobes linked by α-helix and belongs to transferrin family. It exists in three isoforms namely lactoferrin-α, lactoferrin-γ, and lactoferrin-β. Lactoferrin corresponds to a molecular weight of 80 kDa.

Especificidade

Rabbit polyclonal anti-lactoferrin antibody reacts with purified lactoferrin and human milk, but does not react with human serum proteins.

Aplicação

Anti-Lactoferrin antibody produced in rabbit has been used in:
  • western blotting
  • indirect immunofluorescence
  • flow cytometry
  • enzyme-linked immunosorbent assay (ELISA)

Ações bioquímicas/fisiológicas

A primary function of lactoferrin is to bind and transport iron ions. However, lactoferrin is also an effective antibacterial, antiviral, antiparasitic, catalytic (RNA degrading), anti-cancer molecule. It elicits anti-inflammatory effects in asthma. It has immunomodulatory and anti-inflammatory functionality and is a potential protein nutraceutical.

forma física

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2

Reconstituição

Reconstitute with 2 ml deionized water.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Expression, purification, and breast cancer cell inhibiting effect of recombinant human lactoferrin C-lobe
Hu L, et al.
Bioscience, Biotechnology, and Biochemistry, 80(2), 257-263 (2016)
Lulu Hu et al.
Scientific reports, 7(1), 4230-4230 (2017-06-28)
Lactoferrin (LTF), an important first line defense molecule against infection, is a common target for humoral autoimmune reactions in humans. Since LTF is a multifunctional protein capable of activating innate immune cells via various surface receptors, we hypothesized that LTF-containing
Alan Grupioni Lourenço et al.
World journal of virology, 3(2), 11-17 (2014-07-16)
To study the effect of seminal plasma on Chemokine (C-C motif) ligand 20 (CCL20) production by epithelial cells and its relationship with lactoferrin. HEC-1A cells, a cell line derived from a monostratified endocervical epithelium, were incubated with samples of seminal
Genetic and epigenetic inactivation of LTF gene at 3p21. 3 in lung cancers
Iijima H, et al.
International Journal of Cancer. Journal International Du Cancer, 118(4), 797-801 (2006)
Neutrophil extracellular traps contain selected antigens of anti-neutrophil cytoplasmic antibodies
Panda R, et al.
Frontiers in Immunology, 8(2), 439-439 (2017)
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