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I8765

Sigma-Aldrich

IgG from mouse serum

technical grade, ≥80% (SDS-PAGE), buffered aqueous solution

Sinônimo(s):

Mouse IgG

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5 MG
R$ 779,00
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R$ 779,00


Disponível para enviar em11 de abril de 2025Detalhes


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5 MG
R$ 779,00
10 MG
R$ 1.356,00
5 X 10 MG
R$ 5.513,00

About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.46

R$ 779,00


Disponível para enviar em11 de abril de 2025Detalhes


Solicite uma grande encomenda

conjugado

unconjugated

grau

technical grade

Ensaio

≥80% (SDS-PAGE)

Formulário

buffered aqueous solution

técnica(s)

ChIP: suitable
immunohistochemistry: suitable

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

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Descrição geral

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections[1]
IgG from mouse serum specifically recognizes IgG from mouse. Mouse IgG is purified from normal mouse serum by fractionation.
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody.[2] A immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense.[3] It is a glycoprotein. IgG is a major class of immunoglobulin.[4] Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE.[4] Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.[5]

Aplicação

Technical grade IgG may be used as an economical alternative to the reagent grade immunoglobulins in applications where high purity is not required. IgG from mouse serum was used as negative control in immunohistochemistry at a concentration of 2 μg/ml.[6] It was used as irrelevant control in chromatin immunoprecipitaion assay (10 μg).[7]

Ações bioquímicas/fisiológicas

Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions.[8] IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.[5]

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.2, containing 15 mM sodium azide

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

nwg

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Oskar Vilhelmsson Timmermand et al.
Theranostics, 9(8), 2129-2142 (2019-06-01)
Androgen ablating drugs increase life expectancy in men with metastatic prostate cancer, but resistance inevitably develops. In a majority of these recurrent tumors, the androgen axis is reactivated in the form of increased androgen receptor (AR) expression. Targeting proteins that
Kamil Jastrzębski et al.
Journal of cell science, 130(3), 577-589 (2016-12-17)
Platelet-derived growth factor receptor β (PDGFRβ) is a receptor tyrosine kinase which upon activation by PDGF-BB stimulates cell proliferation, migration and angiogenesis. Ligand binding induces intracellular signaling cascades but also internalization of the receptor, eventually resulting in its lysosomal degradation.
Anne L Sapiro et al.
Cell reports, 31(7), 107654-107654 (2020-05-21)
Adenosine-to-inosine RNA editing, catalyzed by adenosine deaminase acting on RNA (ADAR) enzymes, alters RNA sequences from those encoded by DNA. These editing events are dynamically regulated, but few trans regulators of ADARs are known in vivo. Here, we screen RNA-binding proteins
The Immunoglobulins: Structure and Function (1998)
The Laboratory Rat (1998)

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