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H6647

Sigma-Aldrich

L-Histidinol dihydrochloride

≥98% (TLC)

Sinônimo(s):

β-Aminoimidazole-4-propanol dihydrochloride, (S)-2-Amino-3-(4-imidazolyl)propanol dihydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C6H11N3O · 2HCl
Número CAS:
1596-64-1
Peso molecular:
214.09
Beilstein:
3914853
Número CE:
216-482-2
Número MDL:
MFCD00078058
Código UNSPSC:
12352209
ID de substância PubChem:
24895755
NACRES:
NA.32

product name

L-Histidinol dihydrochloride, ≥98 (TLC)

Ensaio

≥98% (TLC)

forma

powder

cor

white to off-white

pf

198-201 °C (dec.) (lit.)

aplicação(ões)

cell analysis

cadeia de caracteres SMILES

Cl[H].Cl[H].N[C@H](CO)Cc1c[nH]cn1

InChI

1S/C6H11N3O.2ClH/c7-5(3-10)1-6-2-8-4-9-6;;/h2,4-5,10H,1,3,7H2,(H,8,9);2*1H/t5-;;/m0../s1

chave InChI

FRCAFNBBXRWXQA-XRIGFGBMSA-N

Informações sobre genes

human ... HRH1(3269)
mouse ... HRH1(15465)
rat ... HRH1(24448)

Procurando produtos similares? Visita Guia de comparação de produtos

Aplicação

L-Histidinol dihydrochloride has been used:
  • as a reagent in urinary metabolite analysis
  • for making DT40 knockout cells, where cells were selected in 1mg/ml histidinol
  • for inducing amino acid deprivation in HepG2 cells

Ações bioquímicas/fisiológicas

Precursor of histamine; reversible inhibitor of protein synthesis.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

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David G Meckes et al.
Virology, 398(2), 208-213 (2010-01-07)
The conserved UL16 tegument protein of herpes simplex virus exhibits dynamic capsid-binding properties with a release mechanism that is triggered during initial virus attachment events. In an effort to understand the capsid association and subsequent release of UL16, we sought
R C Warrington
Biochemistry and cell biology = Biochimie et biologie cellulaire, 70(5), 365-375 (1992-05-01)
Human cancer chemotherapy is limited by two major problems: the failure of commonly used anticancer drugs to act against tumor cells in a specific manner and the ability of malignant cells to resist killing by antineoplastic agents. Experimentally, both of
Fouzia Sadiq et al.
Nutrition & metabolism, 5, 5-5 (2008-02-14)
Intravenous infusions of glucose and amino acids increase both nitrogen balance and muscle accretion. We hypothesised that co-infusion of glucose (to stimulate insulin) and essential amino acids (EAA) would act additively to improve nitrogen balance by decreasing muscle protein degradation
Yannick Hövelmann et al.
Journal of agricultural and food chemistry, 67(13), 3670-3678 (2019-03-13)
Imidazole alkaloids represent a rather small group of alkaloids and are assumed not to be of significance to the human food chain so far. In this study, novel imidazole alkaloids occurring in tomato products were synthesized and structurally characterized by
Ana Luísa De Sousa-Coelho et al.
Journal of lipid research, 54(7), 1786-1797 (2013-05-11)
Lipogenic gene expression in liver is repressed in mice upon leucine deprivation. The hormone fibroblast growth factor 21 (FGF21), which is critical to the adaptive metabolic response to starvation, is also induced under amino acid deprivation. Upon leucine deprivation, we
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