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G1506

Sigma-Aldrich

Guanylyl(3′→5′)cytidine ammonium salt

Sinônimo(s):

GpC

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About This Item

Fórmula linear:
C19H25N8O12P · NH3
Número CAS:
98046-67-4
Peso molecular:
605.45
Número MDL:
MFCD00058649
Código UNSPSC:
41106305
ID de substância PubChem:
24895064

forma

solid

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

N.NC1=NC(=O)c2ncn(C3OC(CO)C(OP(O)(=O)OCC4OC(C(O)C4O)N5C=CC(N)=NC5=O)C3O)c2N1

InChI

1S/C19H25N8O12P.H3N/c20-8-1-2-26(19(33)23-8)16-11(30)10(29)7(38-16)4-36-40(34,35)39-13-6(3-28)37-17(12(13)31)27-5-22-9-14(27)24-18(21)25-15(9)32;/h1-2,5-7,10-13,16-17,28-31H,3-4H2,(H,34,35)(H2,20,23,33)(H3,21,24,25,32);1H3

chave InChI

PPSONIOCBRREER-UHFFFAOYSA-N

Aplicação

Guanylyl(3′5′)cytidine is an oligonucleotide pyrimidine dimer used as a substrate to study the specificity and kinetics of various RNases such as RNase T1 and its mutations.

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Snawar Hussain et al.
Acta tropica, 173, 136-146 (2017-06-14)
Zika virus is a zoonotic pathogen, which have made frequent incursion into the human population in Africa and South East Asia over the course of several decades but never reached to the pandemic proportions until the most recent outbreak. Viruses
Yang Wang et al.
Nature communications, 12(1), 1247-1247 (2021-02-25)
Extensive epigenetic reprogramming occurs during preimplantation embryo development. However, it remains largely unclear how the drastic epigenetic reprogramming contributes to transcriptional regulatory network during this period. Here, we develop a single-cell multiomics sequencing technology (scNOMeRe-seq) that enables profiling of genome-wide
Francisco Requena et al.
Scientific reports, 9(1), 8140-8140 (2019-06-01)
Recent technical advances highlight that to understand mammalian development and human disease we need to consider transcriptional and epigenetic cell-to-cell differences within cell populations. This is particularly important in key areas of biomedicine like stem cell differentiation and intratumor heterogeneity.
Holger Kruse et al.
Journal of chemical theory and computation, 15(1), 95-115 (2018-11-30)
The stacking energies of 10 unique B-DNA base-pair steps were calculated with highly accurate quantum chemistry and used as reference values in a thorough benchmark of (dispersion-corrected) DFT, wave function methods, tight-binding methods, and different force fields, including charge variants
Elena Loreti et al.
Plant physiology, 182(1), 287-300 (2019-07-31)
In plants, hypoxia can be induced by submergence, and the lack of oxygen impairs mitochondrial respiration, thus affecting the plant's energy status. Hypoxia has major effects on gene expression; these changes induce key responses that help meet the needs of
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