0.1 M HCl: soluble (Solutions should be freshly prepared.) H2O: moderately soluble (Solutions should be freshly prepared.) aqueous base: unstable ethanol: soluble (Solutions should be freshly prepared.)
Although several studies have shown that L-threo3,4-dihydroxyphenylserine (DOPS) may provide a neuroprotective effect against ischemic brain damage, its protective mechanism is not fully understood. Glutamate release and hippocampal blood flow in ischemia with administration of DOPS were investigated to elucidate
Cellular and molecular life sciences : CMLS, 53(8), 646-651 (1997-08-01)
The effects of some noradrenergic agents, phenobarbitone, diazepam and phenytoin on seizures produced by propranolol were investigated in mice. Isoprenaline and DL-threo-3,4-dihydroxyphenylserine (DOPS) effectively antagonized the seizures elicited by propranolol. Pargyline and imipramine significantly attenuated propranolol-induced seizures and also significantly
Journal of neurochemistry, 70(6), 2468-2476 (1998-05-29)
Mice with a targeted disruption of the dopamine beta-hydroxylase (DBH) gene are unable to synthesize norepinephrine (NE) and epinephrine. These mice have elevated levels of dopamine in most tissues, although the levels are only a fraction of those normally found
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