C1159
L-Cycloserine
Sinônimo(s):
(S)-4-Amino-3-isoxazolidone
Faça loginpara ver os preços organizacionais e de contrato
Selecione um tamanho
10 MG
R$ 378,00
25 MG
R$ 677,00
100 MG
R$ 1.640,00
250 MG
R$ 3.432,00
Selecione um tamanho
Alterar visualização
10 MG
R$ 378,00
25 MG
R$ 677,00
100 MG
R$ 1.640,00
250 MG
R$ 3.432,00
About This Item
Fórmula empírica (Notação de Hill):
C3H6N2O2
Número CAS:
Peso molecular:
102.09
Beilstein:
80799
Número CE:
Número MDL:
Código UNSPSC:
12352202
eCl@ss:
32160406
ID de substância PubChem:
NACRES:
NA.77
Produtos recomendados
Ensaio
≥95% (TLC)
Formulário
powder
pf
146 °C
solubilidade
H2O: 50 mg/mg protein
temperatura de armazenamento
−20°C
cadeia de caracteres SMILES
N[C@H]1CONC1=O
InChI
1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m0/s1
chave InChI
DYDCUQKUCUHJBH-REOHCLBHSA-N
Procurando produtos similares? Visita Guia de comparação de produtos
Ações bioquímicas/fisiológicas
Blocks sphingosine biosynthesis by inhibition of ketosphinganine synthetase. Cytotoxicity toward neuroblastoma and medulloblastoma cells mediated by suppression of ganglioside synthesis.[1]
L-cycloserine is a potent inhibitor of serine palmitoyltransferase, the first step of sphingolipid synthesis.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
Escolha uma das versões mais recentes:
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Os clientes também visualizaram
Elisa Caiola et al.
Cells, 9(8) (2020-07-29)
Non-small-cell lung cancer (NSCLC) cell lines vary in their sensitivity to glutaminase inhibitors, so it is important to identify the metabolic assets underling their efficacy in cancer cells. Even though specific genetic lesions such as in KRAS and LKB1 have
David M Pereira et al.
Marine drugs, 12(1), 54-68 (2013-12-26)
We describe the effect of a chemically characterized lipophilic extract obtained from Marthasterias glacialis L. against human breast cancer (MCF-7) and human neuroblastoma (SH-SY5Y) cell lines. Evaluation of DNA synthesis revealed that both cell lines were markedly affected in a
J Cinatl et al.
Anticancer research, 19(6B), 5349-5354 (2000-03-04)
Human neuroblastoma and medulloblastoma express abnormal ganglioside patterns especially GD2 and GM2 which are important for tumour growth. We tested the effects of L-cycloserine (L-CS), a potent inhibitor of synthesis of glycosphingolipids, on the growth, viability and expression of GD2
Geraldine Rath et al.
The international journal of biochemistry & cell biology, 41(5), 1165-1172 (2008-11-26)
Doxorubicin and camptothecin are two cytotoxic chemotherapeutic agents triggering apoptosis in various cancer cells, including thyroid carcinoma cells. Recent studies revealed a critical role of ceramide in chemotherapy and suggested that anti-cancer drugs may kill tumor cells through sphingomyelinase activation.
Domenico Sergi et al.
Nutritional neuroscience, 23(4), 321-334 (2018-07-24)
A high-fat diet induces hypothalamic inflammation in rodents which, in turn, contributes to the development of obesity by eliciting both insulin and leptin resistance. However, the mechanism by which long-chain saturated fatty acids trigger inflammation is still contentious. To elucidate
Active Filters
Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.
Entre em contato com a assistência técnica
