Following reconstitution at 25 mg/mL in 0.1 M Acetic acid, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C. The stability of dilute solutions has not been determined, however, Bradykinin fragment 1 - 7, (B4181) is part of a set of standards for Maldi-MS calibration (MSCAL1). In this application, the solution is diluted to 10 pmol/uL and stored at -20°C for 1 month. One may infer that dilute solutions of the whole molecule would be comparably stable when diluted and stored frozen.
B3259
Bradykinin acetate salt
powder, ≥98% (HPLC)
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1 MG
R$ 284,00
5 MG
R$ 764,00
10 MG
R$ 969,00
25 MG
R$ 2.144,00
100 MG
R$ 5.019,00
About This Item
Fórmula empírica (Notação de Hill):
C50H73N15O11 · xC2H4O2
Número CAS:
Peso molecular:
1060.21 (free base basis)
Número CE:
Número MDL:
Código UNSPSC:
12352106
NACRES:
NA.32
Produtos recomendados
grau
for analytical purposes
Ensaio
≥98% (HPLC)
Formulário
powder
condição de armazenamento
desiccated
cor
white
solubilidade
0.1 M acetic acid: 25 mg/mL, clear, colorless
nº de adesão UniProt
temperatura de armazenamento
−20°C
cadeia de caracteres SMILES
N2([C@@H](CCC2)C(=O)NCC(=O)N[C@@H](Cc5ccccc5)C(=O)N[C@@H](CO)C(=O)N3[C@@H](CCC3)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)C(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CCCN=C(N)N
InChI
1S/C50H73N15O11/c51-32(16-7-21-56-49(52)53)45(72)65-25-11-20-39(65)47(74)64-24-9-18-37(64)43(70)58-28-40(67)59-34(26-30-12-3-1-4-13-30)41(68)62-36(29-66)46(73)63-23-10-19-38(63)44(71)61-35(27-31-14-5-2-6-15-31)42(69)60-33(48(75)76)17-8-22-57-50(54)55/h1-6,12-15,32-39,66H,7-11,16-29,51H2,(H,58,70)(H,59,67)(H,60,69)(H,61,71)(H,62,68)(H,75,76)(H4,52,53,56)(H4,54,55,57)/t32-,33-,34-,35-,36-,37-,38-,39-/m0/s1
chave InChI
QXZGBUJJYSLZLT-FDISYFBBSA-N
Informações sobre genes
human ... KNG1 (includes EG:3827)
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Categorias relacionadas
Amino Acid Sequence
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
Aplicação
Ações bioquímicas/fisiológicas
Activates pain receptors; induces smooth muscle contraction; activates Ca2+-dependent nitric oxide synthetase; increases capillary permeability.
Bradykinin is a pro-inflammatory peptide that acts through G-protein-coupled receptors. It activates sphingolipid metabolism. Fibroblasts treated with bradykinin produce a rapid and important increase in ceramide which is followed by a transient rise in sphingosine content. The peptide also increases ceramide cellular content by rapidly mobilizing neutral glycolipids. Bradykinin plays an important role in the regulation of fluid and electrolyte balance, smooth muscle contraction, vasodilation and capillary permeability. The bradykinin potentiators, which possess no bradykinin activity themselves, enhance the activity of bradykinin.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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How should a solution of bradykinin acetate salt in 0.1M acetic acid be stored? Can it be further diluted in an aqueous buffer?
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