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B2754

Sigma-Aldrich

Betaine monohydrate

≥99%

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500 G
R$ 1.333,00
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500 G
R$ 1.333,00
1 KG
R$ 2.300,00

About This Item

Fórmula linear:
(CH3)3N+CH2COO- · H2O
Número CAS:
Peso molecular:
135.16
Beilstein:
3626258
Número CE:
Número MDL:
Código UNSPSC:
12352204
ID de substância PubChem:
NACRES:
NA.83

R$ 1.333,00


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fonte biológica

synthetic

Ensaio

≥99%

Formulário

powder or crystals

solubilidade

water: 50 mg/mL, clear, colorless

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

O.C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2.H2O/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H2

chave InChI

NJZRLXNBGZBREL-UHFFFAOYSA-N

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Descrição geral

Betaine is a zwitterionic quaternary ammonium compound and is mainly present in animals, microorganisms and plants. It is one of the main constituent of several food items like wheat, shellfish, spinach and sugar beets. It is also termed as trimethylglycine, lycine, glycine betaine and oxyneurine. Betaine is a methyl derivative of glycine. It has a molecular mass of 117.2.[1]

Aplicação

Betaine monohydrate has been used:
  • in the preparation of KLA buffer to perform polymerase chain reaction (PCR)[2]
  • to study the its effects on Km and Vmax of human aldose reductase[3]
  • to study its effects on the growth of A549 lung cancer both in vitro and in vivo[4]

Ações bioquímicas/fisiológicas

Betaine, as an osmolyte helps to guard the cells, proteins and enzymes from environmental stress. It also acts as a methyl donor to involve in the methionine cycle.[1]
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.[5]

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Os clientes também visualizaram

Study of the effects of betaine and/or C-phycocyanin on the growth of lung cancer A549 cells in vitro and in vivo
Bingula R, et al.
Journal of Oncology, 2016 (2016)
Anirban Purohit et al.
Biophysical journal, 120(1), 73-85 (2020-11-23)
Sliding clamps are oligomeric ring-shaped proteins that increase the efficiency of DNA replication. The stability of the Escherichia coli β-clamp, a homodimer, is particularly remarkable. The dissociation equilibrium constant of the β-clamp is of the order of 10 pM in
Wnt-dependent β-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis.
Surendran K, et al.
Journal of the American Society of Nephrology, 16(8), 2373-2384 (2005)
Factors affecting counteraction by methylamines of urea effects on aldose reductase
Burg MB, et al.
Proceedings of the National Academy of Sciences of the USA, 96(11), 6517-6522 (1999)
Stuart A S Craig
The American journal of clinical nutrition, 80(3), 539-549 (2004-08-24)
Betaine is distributed widely in animals, plants, and microorganisms, and rich dietary sources include seafood, especially marine invertebrates ( approximately 1%); wheat germ or bran ( approximately 1%); and spinach ( approximately 0.7%). The principal physiologic role of betaine is

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