A9285
α1-Antichymotrypsin from human plasma
≥92.5% (SDS-PAGE), lyophilized powder
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0.1 MG
R$ 1.721,00
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0.1 MG
R$ 1.721,00
About This Item
Produtos recomendados
fonte biológica
human plasma
Nível de qualidade
Ensaio
≥92.5% (SDS-PAGE)
Formulário
lyophilized powder
peso molecular
55-66 kDa
técnica(s)
microbiological culture: suitable
nº de adesão UniProt
temperatura de armazenamento
−20°C
Informações sobre genes
human ... SERPINA3(12)
Descrição geral
Aplicação
α1-Antichymotrypsin from human plasma has been used as a component in yeast extract peptone dextrose broth (YEPD) for biofilm dispersion assays.[4]
Ações bioquímicas/fisiológicas
α1-Antichymotrypsin (α1-ACT) can block the functions of various serine proteases like chymotrypsin and cathepsin G.[1] It serves as a potential therapeutic target of endometrial carcinoma (EC).[2]
Specific inhibitor of chymotrypsin-like serine proteases.
Specific inhibitor of chymotrypsin-like serine proteases. Promotes amyloid-β polymerization in vitro and in vivo. Levels in plasma and cerebrospinal fluid have been found to correlate with progression of dementia in Alzheimer′s patients and induce phosphorylation of tau protein in neurons.
Embalagem
Package size based on protein content.
forma física
Lyophilized powder containing Tris buffer salt and NaCl.
Exoneração de responsabilidade
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Human plasma proteinase inhibitors.
J Travis et al.
Annual review of biochemistry, 52, 655-709 (1983-01-01)
Is Alpha-1 Antichymotrypsin Gene Polymorphism a Risk Factor for Primary Intracerebral Hemorrhage? A Case-Control Study and Meta-Analysis
Hu X, et al.
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 2149-2149 (2015)
SERPINA3 promotes endometrial cancer cells growth by regulating G2/M cell cycle checkpoint and apoptosis.
Yang GD
International Journal of Clinical and Experimental Pathology, 7(4), 1348-1358 (2014)
Up-regulation of SERPINA3 correlates with high mortality of melanoma patients and increased migration and invasion of cancer cells.
Zhou J, et al.
Oncotarget, 8(12), 18712-18712 (2017)
Brandon M Childers et al.
Infection and immunity, 81(11), 4112-4120 (2013-08-28)
Biofilm formation and persistence are essential components for the continued survival of pathogens inside the host and constitute a major contributor to the development of chronic wounds with resistance to antimicrobial compounds. Understanding these processes is crucial for control of
Artigos
Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.
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