76216
Papain from Carica papaya
solution, light brown, ≥10 U/mg protein (~25 mg/ml)
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50 MG
R$ 546,00
250 MG
R$ 1.731,00
1 G
R$ 6.251,00
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Alterar visualização
50 MG
R$ 546,00
250 MG
R$ 1.731,00
1 G
R$ 6.251,00
About This Item
Produtos recomendados
fonte biológica
papaya
Nível de qualidade
Formulário
solution
atividade específica
≥10 U/mg protein (~25 mg/ml)
peso molecular
Mr ~23000
técnica(s)
cell culture | mammalian: suitable
single cell analysis: suitable
cor
light brown
temperatura de armazenamento
2-8°C
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Descrição geral
Papain is a proteolytic enzyme and is naturally occurring in papaya (Carica papaya L.). It is obtained from the latex of cut unripe papaya. Papain belongs to the cysteine proteinase family. It is a globular, single-chain protein composed of four disulfide bridges and catalytically essential residues. Papain consists of an all α-domain and anti-parallel β-sheet domain.[1]
Aplicação
Papain from Carica papaya has been used:
Papain is used as a meat tenderizer. It′s also used to break up tissue in the preparation of primary cell cultures.
Ações bioquímicas/fisiológicas
Papain is a cysteine protease that cleaves peptide bonds and is known to cleave the Fc portion of antibodies.
Papain plays an important role in many biological processes in many living organisms. It exhibits proteolytic activity against proteins, amino-acid esters and amide links, and short-chain peptides. Papain preferentially cleaves the peptide bonds of basic amino acids such as arginine, phenylalanine, and lysine. It has a wide range of applications in drug discovery, pharmaceutical, food[1], baking, and dairy industries.[5]
Definição da unidade
1 U corresponds to the amount of enzyme which hydrolyzes 1 μmol N-benzoyl-L-arginine ethyl ester (BAEE, Cat. No. 12880) per minute at pH 6.2 and 25°C
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
Órgãos-alvo
Respiratory system
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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