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302-05A

Sigma-Aldrich

Human Pulmonary Artery Endothelial Cells: HPAEC, adult

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About This Item

Código UNSPSC:
41106514
NACRES:
NA.81

fonte biológica

human pulmonary artery (normal)

Nível de qualidade

100

embalagem

pkg of 500,000 cells

fabricante/nome comercial

Cell Applications, Inc

modo de crescimento

Adherent

cariótipo

2n = 46

morfologia

Endothelial

técnica(s)

cell culture | mammalian: suitable

doença(s) relevante(s)

diabetes; cardiovascular diseases

Condições de expedição

dry ice

temperatura de armazenamento

−196°C

Categorias relacionadas

Descrição geral

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HPAEC provide an excellent model system to study many aspects of cardiovascular function and disease, including diabetes-associated complications, mechanisms of endothelial dysfunction caused by environment, oxidative stress, hypoxia and inflammation, as well as mode of action of various natural compounds and drug candidates.

Origem de linhagem celular

Artery

Aplicação

cardiovascular function, screening of drug candidates, angiogenesis, vasodilator function, transport of deoxygenated bloood from heart to lungs

Componentes

Basal Medium containing 10% FBS & 10% DMSO

Nota de preparo

  • 2nd passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 15 doublings

Rotina de subcultura

Please refer to the HPAEC Culture Protocol.

Exoneração de responsabilidade

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

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Mauro Lago-Docampo et al.
Frontiers in cardiovascular medicine, 9, 823133-823133 (2022-03-15)
Pulmonary Arterial Hypertension (PAH) is a rare disease caused by the obliteration of the pulmonary arterioles, increasing pulmonary vascular resistance and eventually causing right heart failure. Endothelin-1 (EDN1) is a vasoconstrictor peptide whose levels are indicators of disease progression and

Protocolos

Human Pulmonary Artery Endothelial Cells (HPAEC) Culture Protocol

Technical information for working with human pulmonary artery endothelial cells including thawing, subculturing and cryopreservation

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