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04231

Sigma-Aldrich

Calcium phosphate dibasic dihydrate

puriss., meets analytical specification of Ph. Eur., BP, USP, 98-102.5%

Sinônimo(s):

Calcium hydrogen phosphate dihydrate

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About This Item

Fórmula linear:
CaHPO4 · 2H2O
Número CAS:
Peso molecular:
172.09
Número CE:
Número MDL:
Código UNSPSC:
51101500
ID de substância PubChem:
NACRES:
NA.21

grau

puriss.

Ensaio

98-102.5%

forma

powder

qualidade

meets analytical specification of Ph. Eur., BP, USP

Impurezas

organic volatile impurities, complies
residual solvents, complies
≤0.003% heavy metals (as Pb)
≤0.1% insoluble in HCl

perda

24.5-26.5% loss on ignition, 800 °C

traços de ânion

carbonate (CO32-): in accordance
chloride (Cl-): ≤200 mg/kg
fluoride (F-): ≤50 mg/kg
sulfate (SO42-): ≤3000 mg/kg

traços de cátion

As: ≤1 mg/kg
Ba:, in accordance (Ph Eur)
Ba:, in accordance (USP)
Fe: ≤300 mg/kg

cadeia de caracteres SMILES

O.O.[Ca++].OP([O-])([O-])=O

InChI

1S/Ca.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+2;;;/p-2

chave InChI

XAAHAAMILDNBPS-UHFFFAOYSA-L

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Aplicação


  • Simultaneous Regulation of the Mechanical/Osteogenic Capacity of Brushite Calcium Phosphate Cement by Incorporating with Poly(ethylene glycol) Dicarboxylic Acid: This research investigates enhancing brushite calcium phosphate cements by adding poly(ethylene glycol) dicarboxylic acid to improve mechanical properties and osteogenic capabilities, applicable in bone regeneration and implant materials. (Gao et al., 2024).

  • Biosurfactant-Assisted Cu Doping of Brushite Coatings: Explores the structural and biofunctional enhancements of brushite coatings through copper doping facilitated by biosurfactants, which could revolutionize surface treatments for biocompatible implants and devices. (Siva Prasad et al., 2024).

  • Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair: This study highlights the application of calcium phosphate dibasic dihydrate in developing protective coatings on magnesium-based implants, significantly advancing orthopedic and dental implant technologies. (Wu et al., 2024).

  • Physiologically Engineered Porous Titanium/Brushite Scaffolds for Critical-Size Bone Defects: Details the design and fabrication of novel scaffolds for treating large bone defects, utilizing a combination of titanium and brushite, highlighting its potential in reconstructive surgery and regenerative medicine. (Abdulaziz et al., 2023).

  • Mechanochemical Synthesis of Cerium Chlorapatite from a Mixture of Cerium Chloride Heptahydrate, Dicalcium Phosphate Dihydrate, and Calcium Hydroxide for Biomedical Application: Focuses on the innovative production of cerium chlorapatite using dicalcium phosphate dihydrate, showcasing its potential in biomedical engineering, especially in drug delivery and tissue engineering. (Otsuka et al., 2024).

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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J M Lausier et al.
Journal of pharmaceutical sciences, 66(11), 1636-1637 (1977-11-01)
The aging of direct compression tablets made using dibasic calcium phosphate dihydrate as the tablet matrix was investigated over 16 weeks. The formula included 6% amaranth as a dye tracer. Two sets of stress storage conditions were used: 25 degrees
Moreton, R. C.
Chemical & Pharmaceutical Bulletin, 868-870 (1996)
Sarsvatkumar Patel et al.
International journal of pharmaceutics, 403(1-2), 109-114 (2010-11-03)
The aim of the study was to develop, compare and validate predictive model for mechanical property of binary systems. The mechanical properties of binary mixtures of ibuprofen (IBN) a poorly compressible high dose drug, were studied in presence of different
Faleh Tamimi et al.
Acta biomaterialia, 8(8), 3161-3169 (2012-04-24)
Dicalcium phosphate dihydrate (brushite) is an osteoconductive biomaterial with great potential as a bioresorbable cement for bone regeneration. Preset brushite cement can be dehydrated into dicalcium phosphate anhydrous (monetite) bioceramics by autoclaving. This heat treatment results in changes in the
Guiling Zhang et al.
Journal of inorganic biochemistry, 113, 1-8 (2012-06-13)
Bisphosphonates (BPs) are a class of synthetic pyrophosphate analogs that can prevent the loss of bone mass, given orally to treat postmenopuasal osteoporosis. It is not clear yet if the benefits of BPs include the possibility of affecting bone apatitic

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