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Y0000376

Dipivefrine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

[2-(2,2-Dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate hydrochloride

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About This Item

Fórmula empírica (Notação de Hill):
C19H29NO5 · HCl
Número CAS:
64019-93-8
Peso molecular:
387.90
Código UNSPSC:
41116107
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

dipivefrine

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

InChI

1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H

chave InChI

VKFAUCPBMAGVRG-UHFFFAOYSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Dipivefrine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H301

Declarações de precaução

P301 + P330 + P331 + P310

Classificações de perigo

Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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F Neu
Bulletin de la Societe belge d'ophtalmologie, (304)(304), 71-76 (2007-08-28)
Cystoid macular edema is a known side effect of different systemic and local medications. Nicotinic acid used as a hypolipemiant agent can cause cystoid macular edema. Local adrenergic antiglaucomatous drugs as well as prostaglandin analogs can induce cystoid macular edema
I Widengård et al.
The British journal of ophthalmology, 82(4), 404-406 (1998-06-26)
To investigate the effect on intraocular pressure (IOP) and aqueous flare of topical applications of latanoprost and dipivefrin alone or combined. 22 patients with open angle glaucoma or ocular hypertension were included in a 4 week open label study. Median
Hojung Choi et al.
Journal of veterinary science, 12(1), 99-101 (2011-03-04)
Color Doppler imaging (CDI) was carried out to evaluate the effects of anti-glaucoma drugs on ophthalmic circulation using CDI-derived resistive index (RI) values. CDI was performed on nine Beagle dogs, and RI values were calculated for the medial long posterior
M R Reyes et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 14(3), 229-237 (1998-07-22)
Previous studies indicate that there may be differences in the protein composition of the aqueous humor in normal and glaucomatous human eyes. These differences in protein composition and concentration may be due to the topical antiglaucoma medications used to treat
Contact dermatitis from dipivefrine with possible cross-reaction to epinephrine.
A Parra et al.
Contact dermatitis, 39(6), 325-326 (1999-01-05)
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