Y0000155

Tramadol hydrochloride

European Pharmacopoeia (EP) Reference Standard

• Sinônimo(s): (±)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride
• Fórmula empírica (Notação de Hill): C₁₆H₂₅NO₂ · HCl
• Número CAS: 36282-47-0
• Peso molecular: 299.84
• Número MDL: MFCD00798507
• Código UNSPSC: 41116107
• ID de substância PubChem: 329830868
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: tramadol
• fabricante/nome comercial: EDQM
• controle de medicamentos: USDEA Schedule IV
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: Cl.COc1cccc(c1)[C@@]2(O)CCCC[C@@H]2CN(C)C
• InChI: 1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1
• chave InChI: PPKXEPBICJTCRU-XMZRARIVSA-N

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Tramadol is a synthetic opiate agonist analgesic, widely used in patients suffering from moderate to severe chronic pain.[1][2] It is considered safe when compared to other opioids. It contributes to the analgesic activity by blocking the nociceptive impulses at the spinal level, inhibiting the norepinephrine and serotonin reuptake.[2]

Aplicação

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Ações bioquímicas/fisiológicas

Opioid analgesic; P450 substrate.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS06,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H301,H336,H411
• Declarações de precaução: P261 - P264 - P271 - P273 - P301 + P310 - P304 + P340 + P312
• Classificações de perigo: Acute Tox. 3 Oral - Aquatic Chronic 2 - STOT SE 3
• Órgãos-alvo: Central nervous system
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable