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SMB01331

Sigma-Aldrich

Dopamine 4-sulfate

Sinônimo(s):

3-Hydroxytyramine-4-O-sulfate, Dopamine 4-O-sulfate, Dopamine sulfate

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About This Item

Fórmula empírica (Notação de Hill):
C8H11NO5S
Número CAS:
Peso molecular:
233.24
Número MDL:
Código UNSPSC:
12352116
NACRES:
NA.77

Ensaio

≥95% (HPLC)

Nível de qualidade

forma

solid

composição

[4-(2-Aminoethyl)-2-hydroxyphenyl]oxidanesulfonic acid

concentração

≤100%

cor

white to beige

pf

265—270.5 °C

grupo funcional

amine

temperatura de armazenamento

−20°C

InChI

1S/C8H11NO5S/c9-4-3-6-1-2-8(7(10)5-6)14-15(11,12)13/h1-2,5,10H,3-4,9H2,(H,11,12,13)

chave InChI

DEKNNWJXAQTLFA-UHFFFAOYSA-N

Descrição geral

Dopamine 4-sulfate is a major circulating plasma metabolite and urinary metabolite of dopamine formed by cytosolic sulfotransferase 1A3 (SULT1A3) from both exogenous and endogenous dopamine. Dopamine 4-sulfate has been shown to bind to the GABA receptor, but not to D1 or D2 dopamine receptors. Dopamine 4-sulfate is 10 times more abundant than isomeric dopamine 3-sulfate and is considered a potential biomarker for banana and other fruits consumption.

Aplicação

Metabolomics research

Outras notas

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Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Katriina Itäaho et al.
Biochemical pharmacology, 74(3), 504-510 (2007-06-06)
SULT1A3 is an enzyme that catalyzes the sulfonation of many endogenous and exogenous phenols and catechols. The most important endogenous substrate is dopamine (DA), which is often used as a probe substrate for SULT1A3. We developed a new method for
N Vázquez-Manjarrez et al.
Genes & nutrition, 15(1), 11-11 (2020-06-21)
Consumption of fruit and vegetable is a key component of a healthy and sustainable diet. However, their accurate dietary assessment remains a challenge. Due to errors in self-reporting methods, the available dietary information is usually biased. Biomarkers of intake constitute
Tina Suominen et al.
PloS one, 10(7), e0133904-e0133904 (2015-07-25)
Dopamine sulfate (DA-3- and DA-4-S) have been determined in the human brain, but it is unclear whether they are locally formed in the central nervous system (CNS), or transported into the CNS from peripheral sources. In the current study, permeation

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