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PHR1816

Supelco

Furosemide Related Compound B

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

4-Chloro-5-sulfamoylanthranilic acid, 4-CHLORO-5- SULFAMOYLANTHRANILIC ACID

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About This Item

Fórmula empírica (Notação de Hill):
C7H7ClN2O4S
Número CAS:
Peso molecular:
250.66
Número CE:
Número MDL:
Código UNSPSC:
41116107
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to USP 1287030

família API

furosemide

Certificado de análise (CofA)

current certificate can be downloaded

embalagem

pkg of 100 mg

pf

267 °C (dec.) (lit.)

aplicação(ões)

pharmaceutical

formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

Nc1cc(Cl)c(cc1C(O)=O)S(N)(=O)=O

InChI

1S/C7H7ClN2O4S/c8-4-2-5(9)3(7(11)12)1-6(4)15(10,13)14/h1-2H,9H2,(H,11,12)(H2,10,13,14)

chave InChI

QQLJBZFXGDHSRU-UHFFFAOYSA-N

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Descrição geral

Furosemide Related Compound B is an impurity of the loop diuretic drug, furosemide. Furosemide is generally used to treat fluid retention in people with heart failure, liver cirrhosis or kidney disease.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Furosemide Related Compound B may be used as a reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC2893 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Pictogramas

Environment

Frases de perigo

Declarações de precaução

Classificações de perigo

Aquatic Chronic 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Visite a Biblioteca de Documentos

The analysis of 4-chloro-5-sulfamoylanthranilic acid in the bulk material and pharmaceutical preparations of furosemide by a high-performance liquid chromatographic method
Rapaka RS, et al.
International Journal of Pharmaceutics, 11(3), 237- 247 (1982)
Furosemide
StatPearls [Internet] (2019)
Furosemide
USP42/NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 41(3), 2006-2006 (2018)

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