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Documentos

BP653

Famotidine

British Pharmacopoeia (BP) Reference Standard

Sinônimo(s):

N′-(Aminosulfonyl)-3-([2-(diaminomethyleneamino)-4-thiazolyl]methylthio)propanamidine

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About This Item

Fórmula empírica (Notação de Hill):
C8H15N7O2S3
Número CAS:
Peso molecular:
337.45
Número MDL:
Código UNSPSC:
41116107
NACRES:
NA.24

grau

pharmaceutical primary standard

Agency

BP

família API

famotidine

forma

solid

prazo de validade

limited shelf life, expiry date on the label

embalagem

pkg of 100 mg

fabricante/nome comercial

BP

condição de armazenamento

OK to freeze

cor

white

pf

162-165 °C

solubilidade

water: insoluble

aplicação(ões)

pharmaceutical
pharmaceutical small molecule

formato

neat

Condições de expedição

ambient

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1

InChI

1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)

chave InChI

XUFQPHANEAPEMJ-UHFFFAOYSA-N

Informações sobre genes

human ... HRH2(3274)

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Descrição geral

Famotidine is a hydrophilic, cationic, histamine H2 receptor antagonist drug that effectively inhibits gastric acid secretion in humans.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Famotidine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Famotidine Tablets
  • Ações bioquímicas/fisiológicas

    H2 histamine receptor antagonist; anti-ulcer agent

    Embalagem

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Outras notas

    Sales restrictions may apply.

    Código de classe de armazenamento

    11 - Combustible Solids

    Classe de risco de água (WGK)

    WGK 2

    Ponto de fulgor (°F)

    Not applicable

    Ponto de fulgor (°C)

    Not applicable


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    Visite a Biblioteca de Documentos

    Famotidine
    British Pharmacopeia
    British Pharmacopoeia, 29(1-2), 247-254 (2020)
    Determination of famotidine in acid reduction tablets by HPTLC and videodensitometry of fluorescence quenched zones
    Campbell AN and Sherma J
    Journal of Liquid Chromatography and Related Technologies, 26(16), 2719-2727 (2003)
    Stability indicating method for famotidine in pharmaceuticals using porous graphitic carbon column
    Helali N and Monser L
    Journal of Separation Science, 31(2) (2008)
    Determination of cimetidine, famotidine, and ranitidine hydrochloride in the presence of their sulfoxide derivatives in pure and dosage forms by high-performance thin-layer chromatography and scanning densitometry
    Kelani KM, et al.
    Journal of AOAC (Association of Official Analytical Chemists) International, 85(5), 1015-1020 (2002)
    Capillary zone electrophoresis method for the determination of famotidine and related impurities in pharmaceuticals
    Helali N, et al.
    Talanta, 74(4) (2008)

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