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Fucoxanthinol

analytical standard

Sinônimo(s):

all-trans-Fucoxanthinol

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About This Item

Fórmula empírica (Notação de Hill):
C40H56O5
Número CAS:
Peso molecular:
616.87
Número MDL:
Código UNSPSC:
85151701
ID de substância PubChem:
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

Ensaio

≥97.0% (HPLC)

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

formato

neat

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

C/C(C=C=C1C(C)(C)C[C@H](O)C[C@]1(O)C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C(C[C@@]2(O3)[C@@]3(C)C[C@@H](O)CC2(C)C)=O

InChI

1S/C40H56O5/c1-28(17-13-18-30(3)21-22-35-36(5,6)23-32(41)25-38(35,9)44)15-11-12-16-29(2)19-14-20-31(4)34(43)27-40-37(7,8)24-33(42)26-39(40,10)45-40/h11-21,32-33,41-42,44H,23-27H2,1-10H3/b12-11+,17-13+,19-14+,28-15+,29-16+,30-18+,31-20+/t22-,32-,33-,38+,39+,40-/m0/s1

chave InChI

NZEPSBGUXWWWSI-VOPPYBPXSA-N

Descrição geral

Fucoxanthinol belongs to the class of carotenoids. It is the primary metabolite of fucoxanthin, a major marine carotenoid isolated from edible brown seaweeds such as Undaria pinnatifida, Hijikia fusiformis, Laminaria japonica and Sargassum fulvellum with various biological functions. Fucoxanthinol is a compound of significant interest as it exhibits various physiological effects. It is a chemotherapeutic agent that is known to inhibit the growth of human colorectal cancer cells.

Aplicação

Fucoxanthinol may be used as an analytical reference standard for the determination of the analyte in rat plasma by chromatography-based techniques.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Simultaneous determination of fucoxanthin and its deacetylated metabolite fucoxanthinol in rat plasma by liquid chromatography-tandem mass spectrometry
Zhang , et al.
Marine drugs, 13(10), 6521- 6536 (2015)
Determination of fucoxanthinol in rat plasma by liquid chromatography-tandem mass spectrometry
Zhang Y, et al.
Journal of Pharmaceutical and Biomedical Analysis, 164(3), 155- 163 (2019)
Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells
Maeda H, et al.
International Journal of Molecular Medicine, 18(1), 147- 152 (2006)
Anticancer effects of fucoxanthin and fucoxanthinol on colorectal cancer cell lines and colorectal cancer tissues
Takahashi K, et al.
Oncology Letters, 10(3), 1463- 1467 (2015)

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