56448

Xanthotoxin

analytical standard

• Sinônimo(s): 8-Methoxypsoralen, 8-MOP, 9-Methoxyfuro[3,2-g][1]benzopyran-7-one, Ammoidin, Methoxsalen, Xanthotoxin
• Fórmula empírica (Notação de Hill): C₁₂H₈O₄
• Número CAS: 298-81-7
• Peso molecular: 216.19
• Beilstein: 196453
• Número CE: 206-066-9
• Número MDL: MFCD00005009
• Código UNSPSC: 85151701
• ID de substância PubChem: 329758209
• NACRES: NA.24

Propriedades

• grau: analytical standard
• Nível de qualidade: 100
• Ensaio: ≥98% (GC)
• prazo de validade: limited shelf life, expiry date on the label
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• pf: 148-150 °C (lit.)
• aplicação(ões): cleaning products; cosmetics; food and beverages; personal care
• Formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: COc1c2OC(=O)C=Cc2cc3ccoc13
• InChI: 1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3
• chave InChI: QXKHYNVANLEOEG-UHFFFAOYSA-N

Descrição

Descrição geral

Xanthotoxin is an allelochemical or a phototoxic allomone mainly found in host plants of black swallowtail.[1] It can have the tendency to induce tolerance towards Α-cypermethrin, a pyrethroid insecticide used for insects like Helicoverpa zea.[2]

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ações bioquímicas/fisiológicas

8-methoxypsoralen (8-MOP) plus ultraviolet A (UVA) irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms. Cultured normal human melanocytes treated with 8-methoxypsoralen and irradiated with ultraviolet A (UVA) formed 8-methoxypsoralen-phospholipid photoadducts that could be substituted for diacylglycerol to activate protein kinase C in a cell-free system. 8-MOP is an inactivator of purified reconstituted cytochrome P450. It also inhibits substance P-induced histamine release from substance P-activated rat peritoneal mast cells by suppressing the rise in [Ca²⁺].

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Outras notas

This compound is commonly found in plants of the genus: angelica carum pimpinella

Informações de segurança

• Pictogramas: GHS08,GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302,H317,H341,H351
• Declarações de precaução: P202 - P261 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Classificações de perigo: Acute Tox. 4 Oral - Carc. 2 - Muta. 2 - Skin Sens. 1
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable