42251
Apigenin
analytical standard
Sinônimo(s):
4′,5,7-Trihydroxyflavone, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
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About This Item
Fórmula empírica (Notação de Hill):
C15H10O5
Número CAS:
Peso molecular:
270.24
Beilstein:
262620
Número CE:
Número MDL:
Código UNSPSC:
85151701
ID de substância PubChem:
NACRES:
NA.24
Produtos recomendados
grau
analytical standard
Nível de qualidade
Ensaio
≥99% (HPLC)
prazo de validade
limited shelf life, expiry date on the label
técnica(s)
HPLC: suitable
gas chromatography (GC): suitable
pf
>300 °C (lit.)
aplicação(ões)
food and beverages
formato
neat
temperatura de armazenamento
2-8°C
cadeia de caracteres SMILES
Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2
InChI
1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
chave InChI
KZNIFHPLKGYRTM-UHFFFAOYSA-N
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Descrição geral
Flavonoids belong to polyphenolic class of compounds. They play crucial role in biological activities which include tumor growth inhibition and chemoprevention. Apigenin is a plant flavonoid mostly used to inhibit ornithine decarboxylase activity and skin tumor.
Apigenin can be found in a wide range of medicinal plants such as Achillea sp., Chamomilla sp., Equisetum sp., Mentha sp., Salix sp., Salvia sp., Silybum sp., Thymus sp., Verbascum sp.
Apigenin can be found in a wide range of medicinal plants such as Achillea sp., Chamomilla sp., Equisetum sp., Mentha sp., Salix sp., Salvia sp., Silybum sp., Thymus sp., Verbascum sp.
Aplicação
It may be used as internal standard for determining peurarin and its metabolites, using LC-ESI-MS/MS, in blood and urine of rats.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Ações bioquímicas/fisiológicas
A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.
Embalagem
Bottomless glass bottle. Contents are inside inserted fused cone.
Outras notas
This compound is commonly found in plants of the genus: achillea mentha pimpinella primula salvia silybum thymus
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
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The purpose of this study was to investigate the anti-inflammatory potential of the natural flavonoid apigenin to mitigate the airway inflammation in asthmatic mice exposed to particulate matter (PM) 2.5, and examine the possible mechanisms involved. BALB/c mice were sensitized
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