27285

Ácido etilenodiamino tetra-acético

meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%

• Sinônimo(s): EDTA, EDTA-Na₂, Edatamil, Edetato, Etilenodiamino tetra-acético dissódico, Sequestrene Na₂
• Fórmula empírica (Notação de Hill): C₁₀H₁₄N₂Na₂O₈ · 2H₂O
• Número CAS: 6381-92-6
• Peso molecular: 372.24
• Beilstein: 3900609
• Número CE: 205-358-3
• Código UNSPSC: 12352107
• ID de substância PubChem: 24856480
• NACRES: NA.77

Propriedades

• Agency: tested according to BP; tested according to Ph. Eur.; tested according to USP
• Nível de qualidade: 200
• conformidade reg.: tested according to FCC
• Ensaio: 99.0-101.0%
• Formulário: crystals
• qualidade: meets analytical specification of Ph. Eur., BP, USP, FCC
• adequação da reação: reagent type: chelator
• Impurezas: residual solvents, complies; ≤0.001% cyanide (CN); ≤0.001% heavy metals (as Pb); ≤0.1% nitrilotriacetic acid (HPLC) (HPLC)
• perda: 8.7-11.4% loss on drying, 200 °C, 3 h
• pH: 4-5 (20 °C, 5%)
• pf: 248 °C (dec.) (lit.)
• solubilidade: water: soluble 100 g/L at 20 °C
• traços de ânion: chloride (Cl^-): ≤100 mg/kg; sulfate (SO₄^2-): ≤500 mg/kg
• traços de cátion: As: ≤1 mg/kg; Ca:, in accordance; Fe: ≤10 mg/kg; Pb: ≤10 mg/kg
• aplicação(ões): pharmaceutical (small molecule)
• cadeia de caracteres SMILES: O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
• chave InChI: OVBJJZOQPCKUOR-UHFFFAOYSA-L

Descrição

Descrição geral

Ethylenediaminetetraacetic acid disodium salt dihydrate, referred to as EDTA is a widely used chelator of divalent cations like Ca⁺². It can inhibit proteases dependent on metal ions, such as, calcium-dependent cysteine proteases. EDTA also acts as a chelator of the Zn ion, inhibiting metalloproteases that require zinc for activity.

Aplicação

Quelante de cátions divalentes. Inibe enzimas, como as metaloproteases, que requerem cátions divalentes para sua atividade.

Ethylenediaminetetraacetic acid disodium salt dihydrate has been used along with Na₂HPO4 and citric acid for preparing Na₂EDTA-McIlvaine buffer.[1] Aqueous solution of Ethylenediaminetetraacetic acid disodium salt dihydrate has also been used for photocatalytic hydrogen production[2]

Outras notas

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Informações de segurança

• Pictogramas: GHS08,GHS07
• Palavra indicadora: Warning
• Frases de perigo: H332,H373
• Declarações de precaução: P260 - P271 - P304 + P340 + P312 - P314 - P501
• Classificações de perigo: Acute Tox. 4 Inhalation - STOT RE 2 Inhalation
• Órgãos-alvo: Respiratory Tract
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)