235989

Brij^® L4

average M_n ~362

• Sinônimo(s): Polyethylene glycol dodecyl ether, Polyoxyethylene (4) lauryl ether
• Fórmula linear: (C₂₀H₄₂O₅)_n
• Número CAS: 9002-92-0
• Número MDL: MFCD00043063
• Código UNSPSC: 12161900
• ID de substância PubChem: 24854130
• NACRES: NA.21

Propriedades

• descrição: non-ionic
• Nível de qualidade: 200
• peso molecular: average M_n ~362
• índice de refração: n20/D 1.451 (lit.)
• densidade: 0.95 g/mL at 25 °C (lit.)
• HLB: 9
• cadeia de caracteres SMILES: CCCCCCCCCCCCOCCOCCOCCOCCO
• InChI: 1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3
• chave InChI: WPMWEFXCIYCJSA-UHFFFAOYSA-N

Descrição

Descrição geral

Brij^® L4 is a non-ionic surfactant. It comprises an alkyl (C12) tail attached to an oxyethylene headgroup.

Aplicação

Brij^® L4 has been used:

• as a surfactant for the synthesis of copper(I) oxide (Cu₂O) spherical nanoparticles using a microemulsion technique
• as a non-ionic surfactant for preparing reverse micelles to synthesize Pt₃Co alloy nanoparticles
• as a surfactant to enhance the efficiency of interfacial coupling of hydrophobic materials and to make hydrogel

Ações bioquímicas/fisiológicas

Brij^® L4 exhibits amphiphilic properties. Brij L4 contains hydrophobic and hydrophilic regions that can form micelles and disperse hydrophobic drugs into the core of micelles. This in turn enhances drug solubility. Brij L4 also elicits a strong inhibitory effect against breast cancer resistance protein (BCRP) mediated drug efflux. It inhibits Taq adsorption better when compared to other commonly used surfactants. Brij L4 supports droplet polymerase chain reaction (PCR) in picoliter reaction volumes at standard Taq concentrations.

Informações legais

Brij is a registered trademark of Croda International PLC

Informações de segurança

• Pictogramas: GHS07,GHS09
• Palavra indicadora: Warning
• Frases de perigo: H302,H315,H319,H411
• Declarações de precaução: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2
• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves