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04936

Sigma-Aldrich

O-(6-Chlorobenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate

≥98.0% (HPLC)

Sinônimo(s):

1-[Bis(dimethylamino)methylen]-5-chlorobenzotriazolium 3-oxide hexafluorophosphate, N,N,N′,N′-Tetramethyl-O-(6-chloro-1H-benzotriazol-1-yl)uronium hexafluorophosphate, HCTU

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About This Item

Fórmula empírica (Notação de Hill):
C11H15ClF6N5OP
Número CAS:
330645-87-9
Peso molecular:
413.69
Número MDL:
MFCD04973268
Código UNSPSC:
12352101
ID de substância PubChem:
329747994
NACRES:
NA.22

Nível de qualidade

200

Ensaio

≥98.0% (HPLC)

forma

powder

adequação da reação

reaction type: Coupling Reactions

Impurezas

≤0.5% water

pf

185-190 °C

aplicação(ões)

peptide synthesis

cadeia de caracteres SMILES

ClC1=CC=C(N([C+](N(C)C)N(C)C)N=[N+]2[O-])C2=C1.F[P-](F)(F)(F)(F)F

InChI

1S/C11H15ClN5O.F6P/c1-15(2)11(16(3)4)18-17-10-7-8(12)5-6-9(10)13-14-17;1-7(2,3,4,5)6/h5-7H,1-4H3;/q+1;-1

chave InChI

ZHHGTMQHUWDEJF-UHFFFAOYSA-N

Aplicação

Reagent for:
Synthesis of near-infrared pH activatable fluorescent probes
Synthesis of human β-amyloid by Fmoc chemistry
Stereoselective Horner-Wadsworth-Emmons olefination
Covalent ligation of fluorescent peptides to quantum dots
Alkylation of human telomere sequence

Outras notas

Tandem Oligonucleotide Synthesis on Solid-Phase Supports for the Production of Multiple Oligonucleotides

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H317

Classificações de perigo

Skin Sens. 1A

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Choose from one of the most recent versions:

Certificados de análise (COA)

Lot/Batch Number
BCCK6682
BCCD7640
BCBZ3421
BCBT4008
BCBR0407V

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Organic & biomolecular chemistry, 8(8), 1885-1893 (2010-05-08)
The synthesis and biological evaluation of ten Michael acceptors containing potential proteasome inhibitors are described. Cellular targets of azide containing inhibitors and were assessed in HEK293T and RAW264.7 cells by a two step labeling strategy, followed by biotin-pulldown, affinity purification
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Water solubilized nanoparticles such as CdSe-ZnS core-shell nanocrystals (quantum dots, QDs) have great potential in bioimaging and sensing applications due to their excellent photophysical properties. However, the efficient modification of QDs with complex biomolecules represents a significant challenge. Here, we
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