03557
Poli(etilenoglicol)
tested according to Ph. Eur., 35,000
Sinônimo(s):
PEG
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About This Item
Fórmula linear:
H(OCH2CH2)nOH
Número CAS:
Número MDL:
Código UNSPSC:
12161900
ID de substância PubChem:
NACRES:
NA.21
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Agency
tested according to Ph. Eur.
Nível de qualidade
Formulário
powder
peso molecular
~35000
solubilidade
aliphatic hydrocarbons: slightly soluble
organic solvents: soluble
aplicação(ões)
pharmaceutical (small molecule)
cadeia de caracteres SMILES
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
chave InChI
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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Aplicação
Poly (ethylene glycol) can be used as a test compound utilized in the overproduction and purification of recombinant Lactobacillus reuteri LrNDT.[1] It can also be used for concentrating the mutants with lower secretion levels used in ELISAs for the quantitation of shgp190 and of the LIF/shgp190 complexes.[2]
Ações bioquímicas/fisiológicas
Nota de preparo
Poly(ethylene glycol) dissolves in many organic solvents and is readily soluble in aromatic hydrocarbons. It also slightly dissolves in aliphatic hydrocarbons.
Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
281.5 °F - closed cup
Ponto de fulgor (°C)
138.6 °C - closed cup
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Jesús Fernández-Lucas et al.
Applied and environmental microbiology, 76(5), 1462-1470 (2010-01-06)
A novel type II nucleoside 2'-deoxyribosyltransferase from Lactobacillus reuteri (LrNDT) has been cloned and overexpressed in Escherichia coli. The recombinant LrNDT has been structural and functionally characterized. Sedimentation equilibrium analysis revealed a homohexameric molecule of 114 kDa. Circular dichroism studies
Juliette Bitard et al.
The Journal of biological chemistry, 278(18), 16253-16261 (2003-02-26)
The leukemia inhibitory factor (LIF) receptor comprises the low affinity binding chain gp190 and the high affinity converter gp130. The ectodomain of gp190 is among the most complex in the hematopoietin receptor family, because it contains two typical cytokine receptor
J L Cleland et al.
Bio/technology (Nature Publishing Company), 10(9), 1013-1019 (1992-09-01)
Previous studies on the refolding of recombinant bovine carbonic anhydrase B (CAB) indicated that polyethylene glycol (PEG) significantly enhanced the recovery of active protein by reducing aggregation. To further test the ability of PEG to enhance refolding, three recombinant human
J L Cleland et al.
The Journal of biological chemistry, 267(19), 13327-13334 (1992-07-05)
Polyethylene glycol (PEG) inhibited aggregation during refolding of bovine carbonic anhydrase B (CAB) through the formation of a nonassociating PEG-intermediate complex. Stoichiometric concentrations of PEG were required for complete recovery of active protein during refolding at aggregating conditions. For example
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
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