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02390

Sigma-Aldrich

1,2-Ethanedithiol

≥98.0% (GC)

Sinônimo(s):

1,2-Dimercaptoethane, Dithioglycol, Ethylene mercaptan

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About This Item

Fórmula linear:
HSCH2CH2SH
Número CAS:
540-63-6
Peso molecular:
94.20
Beilstein:
505946
Número CE:
208-752-3
Número MDL:
MFCD00004892
Código UNSPSC:
12352100
ID de substância PubChem:
329747425
NACRES:
NA.22
Preço e disponibilidade não estão disponíveis no momento.

densidade de vapor

>1 (vs air)

Nível de qualidade

200

pressão de vapor

4.8 mmHg ( 20 °C)

Ensaio

≥98.0% (GC)

Formulário

liquid

índice de refração

n20/D 1.558 (lit.)
n20/D 1.558

p.e.

144-146 °C (lit.)

pf

−41 °C (lit.)

densidade

1.123 g/mL at 25 °C (lit.)

grupo funcional

thiol

cadeia de caracteres SMILES

SCCS

InChI

1S/C2H6S2/c3-1-2-4/h3-4H,1-2H2

chave InChI

VYMPLPIFKRHAAC-UHFFFAOYSA-N

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Descrição geral

1,2-Ethanedithiol (EDT) is an organosulfur compound that is used as an organic building block in chemical synthesis. It is also used as a ligand for metal ions to prepare metal complexes.

Aplicação

1,2-Ethanedithiol can be used to synthesize:      
  • 1,3-Dithiolanes by reacting with aldehydes or ketones.
  • Dithiazepan-3-yl-alkanoic acids by cyclocondensation reaction with amino acids and formaldehyde.
  • EDT can also be used as a scavenger in solid phase peptide synthesis for the efficient deprotection of the peptide resin.

Pictogramas

FlameSkull and crossbones
GHS02,GHS06

Palavra indicadora

Danger

Frases de perigo

H226,H301,H310 + H330

Classificações de perigo

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

111.2 °F - closed cup

Ponto de fulgor (°C)

44 °C - closed cup

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
STBL2345
STBL0954
STBK6010
STBK2077
STBJ6018

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P Fadden et al.
Analytical biochemistry, 225(1), 81-88 (1995-02-10)
Reaction conditions were defined for the selective quantitative derivatization and fluorophore labeling of phosphoserine residues on peptides and proteins. Phosphoserine was derivatized with 1,2-ethanedithiol using a modification of the reaction conditions defined by R. C. Clark and J. Dijkstra (1967)
Majed Halwani et al.
International journal of pharmaceutics, 373(1-2), 141-146 (2009-05-12)
Recurrent pulmonary infection and inflammation are major risk factors for high morbidity and mortality in patients with cystic fibrosis (CF). As such, frequent antibiotic use and drug resistant bacterial strains are main concerns in individuals with CF. Bacterial virulence and
C H Sissons et al.
Oral microbiology and immunology, 15(5), 317-324 (2001-01-12)
Urease synthesis in Streptococcus salivarius is induced by an acid environment, carbohydrate and a high growth rate. We now report that both cysteine and sulfide above 1 mM strongly suppress S. salivarius urease levels. Close structural relatives of cysteine (cysteamine
Philip Domenico et al.
Peptides, 25(12), 2047-2053 (2004-12-02)
Staphylococci are a major cause of infections associated with indwelling medical devices. Biofilm formation on these devices adds to the antibiotic resistance seen among clinical isolates. RNAIII-inhibiting peptide (RIP) is a heptapeptide that inhibits staphylococcal pathogenesis, including biofilm formation, by
Eunice F S Vieira et al.
Journal of colloid and interface science, 289(1), 42-47 (2005-07-13)
The nature of interactions between metal ions Ag(I), Hg(II), Cu(II) and chitosan derivative of 1,2-ethanedithiol, QTDT, was investigated by isothermal calorimetry using the membrane breaking technique. Simultaneous determination of thermal effects, Q(int), and amount of cation that interacts, n(int), are
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