Potassium bromate (KBrO(3)) is a widely used food additive, a water disinfection by-product and a known nephrotoxic agent. The effect of KBrO(3) on rat blood, especially on the anti-oxidant defense system, was studied in this work. Animals were given a
Environmental health perspectives, 87, 309-335 (1990-07-01)
Potassium bromate (KBrO3) is an oxidizing agent that has been used as a food additive, mainly in the bread-making process. Although adverse effects are not evident in animals fed bread-based diets made from flour treated with KBrO3, the agent is
Fanconi anemia (FA) and ataxia telangiectasia (AT) share common traits such chromosomal instability and proneness to hematological cancers. Both AT and FA cell lines, and patients, are characterized by abnormally high levels of oxidative stress markers. The key FA protein
BMC complementary and alternative medicine, 12, 204-204 (2012-11-03)
Rutin, a polyphenolic flavonoid, was investigated for its protective effects against the KBrO(3) induced renal injuries in rat. Group I was control (untreated), group II was given saline 0.5 ml/kg bw (0.9% NaCl), group III was administered KBrO(3) (20 mg/kg
Archives of toxicology, 86(11), 1741-1751 (2012-07-05)
Potassium bromate (KBrO(3)) is an oxidising agent that has been widely used in the food and cosmetic industries. It has shown to be both a nephrotoxin and a renal carcinogen in in vivo and in vitro models. Here, we investigated
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