10602370001

Plasmin, bovine

from bovine plasma

• Sinônimo(s): Plasmin
• Número da licença da enzima: 3.4.21.7 (BRENDA, IUBMB)
• Código UNSPSC: 12352204

Propriedades

• fonte biológica: bovine plasma
• forma: suspension
• atividade específica: ≥2 units/mg protein (At 25 °C with Chromozym PL as the substrate.)
• peso molecular: M_r ~85 kDa
• embalagem: pkg of 1 mL (5 U)
• fabricante/nome comercial: Roche
• pH ideal: 8.9
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C

Descrição

Descrição geral

Plasmin is derived from the proteolytic cleavage of its precursor plasminogen. Human Plasmin is made up of two polypeptide chains. The polypeptide chains are connected via disulfide bridges.

Especificidade

Serine endopeptidase that hydrolyzes peptide and ester bonds at the carboxylic side of Lys or Arg; more selective than trypsin.

Aplicação

Plasmin from bovine has been used as a standard for assessing plasmin biosensors and for proteolytic assays.

Ações bioquímicas/fisiológicas

Plasmin plays an important role in proteolysis and fibrinolysis. It possesses inflammatory activity. Plasmin is also involved in the hydrolysis of peptide bonds following arginine or lysine. It also cleaves hormones like glucagon, thrombopoietin and growth hormones. Plasmin plays a role in cleavage of complement factors like C3 and C5, coagulation factors V and VIII, matrix proteins, growth factors, E-cadherins and metalloproteinase.

forma física

Suspension in 3.2 M ammonium sulfate solution

Outras notas

For life science research only. Not for use in diagnostic procedures.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): does not flash
• Ponto de fulgor (°C): does not flash